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    glb-33 GLOBIN domain-containing protein;G_PROTEIN_RECEP_F1_2 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 178627, updated on 9-Dec-2024

    Summary

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    Official Symbol
    glb-33
    Official Full Name
    GLOBIN domain-containing protein;G_PROTEIN_RECEP_F1_2 domain-containing protein
    Primary source
    WormBase:WBGene00022284
    Locus tag
    CELE_Y75B7AL.1
    See related
    AllianceGenome:WB:WBGene00022284
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable neuropeptide receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in neurons and somatic nervous system. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See glb-33 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    7
    Sequence:
    Chromosome: V; NC_003283.11 (1352126..1356594)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Protein amnionless Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene C2 domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The effect of pH and nitrite on the haem pocket of GLB-33, a globin-coupled neuronal transmembrane receptor of Caenorhabditis elegans. Van Brempt N, et al. Biochim Biophys Acta Proteins Proteom, 2023 Jul 1. PMID 37004900
    2. A globin domain in a neuronal transmembrane receptor of Caenorhabditis elegans and Ascaris suum: molecular modeling and functional properties. Tilleman L, et al. J Biol Chem, 2015 Apr 17. PMID 25666609, Free PMC Article
    3. The Caenorhabditis globin gene family reveals extensive nematode-specific radiation and diversification. Hoogewijs D, et al. BMC Evol Biol, 2008 Oct 9. PMID 18844991, Free PMC Article
    4. Wide diversity in structure and expression profiles among members of the Caenorhabditis elegans globin protein family. Hoogewijs D, et al. BMC Genomics, 2007 Oct 4. PMID 17916248, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The effect of pH and nitrite on the haem pocket of GLB-33, a globin-coupled neuronal transmembrane receptor of Caenorhabditis elegans.
      Title: The effect of pH and nitrite on the haem pocket of GLB-33, a globin-coupled neuronal transmembrane receptor of Caenorhabditis elegans.
    2. The globin domain of GLB-33 may serve as a highly sensitive oxygen sensor and/or as a nitrite reductase.
      Title: A globin domain in a neuronal transmembrane receptor of Caenorhabditis elegans and Ascaris suum: molecular modeling and functional properties.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables neuropeptide receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxygen binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in neuropeptide signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    GLOBIN domain-containing protein;G_PROTEIN_RECEP_F1_2 domain-containing protein
    NP_001300285.1
    • Confirmed by transcript evidence
    NP_001300286.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      1352126..1356594
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001313356.3 → NP_001300285.1  G_PROTEIN_RECEP_F1_2 domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3AT43
      Conserved Domains (1) summary
      cd01040
      Location:386 → 531
      Mb_like; myoglobin_like; M family globin domain

    2. NM_001313357.3 → NP_001300286.1  GLOBIN domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3AVE6
      Conserved Domains (1) summary
      cd01040
      Location:302 → 447
      Mb_like; myoglobin_like; M family globin domain
    Nucleotide Protein
    Heading Accession and Version

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