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    Y69A2AR.19 Protein-tyrosine-phosphatase [ Caenorhabditis elegans ]

    Gene ID: 177036, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y69A2AR.19
    Official Full Name
    Protein-tyrosine-phosphatase
    Primary source
    WormBase:WBGene00022090
    Locus tag
    CELE_Y69A2AR.19
    See related
    AllianceGenome:WB:WBGene00022090
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in protein dephosphorylation. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y69A2AR.19 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    11
    Sequence:
    Chromosome: IV; NC_003282.8 (2488820..2494186)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Phospholipase A2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Coiled-coil domain-containing protein 12

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Protein-tyrosine-phosphatase
    NP_001294610.1
    • Confirmed by transcript evidence
    NP_001360613.1
    • Confirmed by transcript evidence
    NP_500211.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      2488820..2494186
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067810.5 → NP_500211.3  Protein-tyrosine-phosphatase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500211.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95XJ2
      Conserved Domains (3) summary
      cd00047
      Location:1019 → 1245
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      pfam00102
      Location:1018 → 1245
      Y_phosphatase; Protein-tyrosine phosphatase
      pfam02206
      Location:172 → 234
      WSN; Domain of unknown function

    2. NM_001307681.3 → NP_001294610.1  Protein-tyrosine-phosphatase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294610.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PMU1
      Conserved Domains (3) summary
      cd00047
      Location:1012 → 1238
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      pfam00102
      Location:1011 → 1238
      Y_phosphatase; Protein-tyrosine phosphatase
      pfam02206
      Location:165 → 227
      WSN; Domain of unknown function

    3. NM_001372744.2 → NP_001360613.1  Protein-tyrosine-phosphatase [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A4V0IL30
      Conserved Domains (3) summary
      TIGR01612
      Location:382 → 762
      235kDa-fam; reticulocyte binding/rhoptry protein
      smart00194
      Location:928 → 1161
      PTPc; Protein tyrosine phosphatase, catalytic domain
      pfam02206
      Location:92 → 154
      WSN; Domain of unknown function
    Nucleotide Protein
    Heading Accession and Version

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