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    taf-3 PHD-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 181704, updated on 9-Dec-2024

    Summary

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    Official Symbol
    taf-3
    Official Full Name
    PHD-type domain-containing protein
    Primary source
    WormBase:WBGene00006384
    Locus tag
    CELE_C11G6.1
    See related
    AllianceGenome:WB:WBGene00006384
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable p53 binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIID complex. Orthologous to human TAF3 (TATA-box binding protein associated factor 3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See taf-3 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    9
    Sequence:
    Chromosome: X; NC_003284.9 (16332435..16346028)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ATP-dependent DNA helicase Neighboring gene ncRNA Neighboring gene Nuclear hormone receptor family member nhr-28 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Intestinal tube formation in Caenorhabditis elegans requires vang-1 and egl-15 signaling. Hoffmann M, et al. Dev Biol, 2010 Mar 15. PMID 20004187
    2. Transcription mechanisms. Blackwell TK, et al. WormBook, 2006 Sep 5. PMID 18050436, Free PMC Article
    3. A transcriptional cofactor regulatory network for the C. elegans intestine. Horowitz BB, et al. G3 (Bethesda), 2023 Jul 5. PMID 37119809, Free PMC Article
    4. Transcriptional regulation. Okkema PG, et al. WormBook, 2005 Dec 23. PMID 18050428, Free PMC Article
    5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables p53 binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of transcription factor TFIID complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    PHD-type domain-containing protein
    NP_001257272.1
    • Confirmed by transcript evidence
    NP_001257273.1
    • Confirmed by transcript evidence
    NP_001257274.1
    • Confirmed by transcript evidence
    NP_001334235.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      16332435..16346028
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001347279.5 → NP_001334235.1  PHD-type domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I6CMF0
      Conserved Domains (2) summary
      smart00576
      Location:11 → 86
      BTP; Bromodomain transcription factors and PHD domain containing proteins
      cd15522
      Location:866 → 911
      PHD_TAF3; PHD finger found in transcription initiation factor TFIID subunit 3 (TAF3)

    2. NM_001270343.4 → NP_001257272.1  PHD-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001257272.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E9P861
      Conserved Domains (2) summary
      smart00576
      Location:11 → 86
      BTP; Bromodomain transcription factors and PHD domain containing proteins
      cd15522
      Location:931 → 976
      PHD_TAF3; PHD finger found in transcription initiation factor TFIID subunit 3 (TAF3)

    3. NM_001270344.3 → NP_001257273.1  PHD-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001257273.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E9P862
      Conserved Domains (1) summary
      cd15522
      Location:272 → 317
      PHD_TAF3; PHD finger found in transcription initiation factor TFIID subunit 3 (TAF3)

    4. NM_001270345.3 → NP_001257274.1  PHD-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001257274.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E9P863
      Conserved Domains (1) summary
      cd15522
      Location:133 → 178
      PHD_TAF3; PHD finger found in transcription initiation factor TFIID subunit 3 (TAF3)
    Nucleotide Protein
    Heading Accession and Version

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