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    F14E5.2 Golgi apparatus protein 1 homolog [ Caenorhabditis elegans ]

    Gene ID: 174342, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F14E5.2
    Official Full Name
    Golgi apparatus protein 1 homolog
    Primary source
    WormBase:WBGene00008800
    Locus tag
    CELE_F14E5.2
    See related
    AllianceGenome:WB:WBGene00008800
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable fibroblast growth factor binding activity. Predicted to be located in membrane. Predicted to be active in Golgi membrane. Orthologous to human GLG1 (golgi glycoprotein 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F14E5.2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    12
    Sequence:
    Chromosome: II; NC_003280.10 (8423953..8428858, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Major facilitator superfamily (MFS) profile domain-containing protein Neighboring gene pseudo Neighboring gene IBB domain-containing protein Neighboring gene ACid Phosphatase family Neighboring gene ACid Phosphatase family

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Direct and heterologous approaches to identify the LET-756/FGF interactome. Popovici C, et al. BMC Genomics, 2006 May 3. PMID 16672054, Free PMC Article
    2. Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules. Marnik EA, et al. Genetics, 2019 Nov. PMID 31506335, Free PMC Article
    3. The conserved histone chaperone LIN-53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans. Müthel S, et al. Aging Cell, 2019 Dec. PMID 31397537, Free PMC Article
    4. In Vivo Interaction Proteomics in Caenorhabditis elegans Embryos Provides New Insights into P Granule Dynamics. Chen JX, et al. Mol Cell Proteomics, 2016 May. PMID 26912668, Free PMC Article
    5. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables fibroblast growth factor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Golgi apparatus protein 1 homolog
    NP_001022087.1
    • Confirmed by transcript evidence
    NP_001367096.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      8423953..8428858 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001381525.2 → NP_001367096.1  Golgi apparatus protein 1 homolog [Caenorhabditis elegans]

      Status: REVIEWED

      Conserved Domains (1) summary
      pfam00839
      Location:219 → 275
      Cys_rich_FGFR; Cysteine rich repeat

    2. NM_001026916.7 → NP_001022087.1  Golgi apparatus protein 1 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001022087.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q19459, Q6BEU4
      Conserved Domains (1) summary
      pfam00839
      Location:219 → 275
      Cys_rich_FGFR; Cysteine rich repeat
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q19459.1

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