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    abu-15 Activated in Blocked Unfolded protein response [ Caenorhabditis elegans ]

    Gene ID: 182136, updated on 9-Dec-2024

    Summary

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    Official Symbol
    abu-15
    Official Full Name
    Activated in Blocked Unfolded protein response
    Primary source
    WormBase:WBGene00004099
    Locus tag
    CELE_C03A7.4
    See related
    AllianceGenome:WB:WBGene00004099
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in endoplasmic reticulum unfolded protein response and pharynx development. Is expressed in pharyngeal muscle cell. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See abu-15 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    2
    Sequence:
    Chromosome: V; NC_003283.11 (5158602..5159907)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene ncRNA Neighboring gene Activated in Blocked Unfolded protein response Neighboring gene Activated in Blocked Unfolded protein response

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cranberry extract standardized for proanthocyanidins promotes the immune response of Caenorhabditis elegans to Vibrio cholerae through the p38 MAPK pathway and HSF-1. Dinh J, et al. PLoS One, 2014. PMID 25062095, Free PMC Article
    2. Toxicogenomic responses of the model organism Caenorhabditis elegans to gold nanoparticles. Tsyusko OV, et al. Environ Sci Technol, 2012 Apr 3. PMID 22372763
    3. Dynamically-expressed prion-like proteins form a cuticle in the pharynx of Caenorhabditis elegans. George-Raizen JB, et al. Biol Open, 2014 Oct 31. PMID 25361578, Free PMC Article
    4. Neuronal GPCR controls innate immunity by regulating noncanonical unfolded protein response genes. Sun J, et al. Science, 2011 May 6. PMID 21474712, Free PMC Article
    5. Unfolded protein response genes regulated by CED-1 are required for Caenorhabditis elegans innate immunity. Haskins KA, et al. Dev Cell, 2008 Jul. PMID 18606143, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in endoplasmic reticulum unfolded protein response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endoplasmic reticulum unfolded protein response IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in pharynx development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Activated in Blocked Unfolded protein response
    NP_504382.1
    • Product from WormBase gene class abu;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      5158602..5159907
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_071981.6 → NP_504382.1  Activated in Blocked Unfolded protein response [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504382.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O16500
    Nucleotide Protein
    Heading Accession and Version

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