Serf1 small EDRK-rich factor 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Serf1provided by RGD
Official Full Name: small EDRK-rich factor 1provided by RGD
Primary source: RGD:1565105
See related: AllianceGenome:RGD:1565105
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1565105
Summary: Predicted to be involved in amyloid fibril formation and protein destabilization. Predicted to be located in cytosol and nucleus. Predicted to be part of protein-containing complex. Orthologous to several human genes including SERF1A (small EDRK-rich factor 1A). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Testes (RPKM 1004.3), Brain (RPKM 65.9) and 2 other tissues See more
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Genomic context

Location:: 2q12

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	2	NC_086020.1 (33210001..33216129)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	2	NC_051337.1 (31475902..31482030)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	2	NC_005101.4 (30345861..30352114)

Chromosome 2 - NC_086020.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH144060 (e-PCR)
- UniSTS:233306

RH134994 (e-PCR)
- UniSTS:218271

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in amyloid fibril formation	ISO Inferred from Sequence Orthology more info
involved_in protein destabilization	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
part_of protein-containing complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: small EDRK-rich factor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.