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    Eif4e3 eukaryotic translation initiation factor 4E family member 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 297481, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Eif4e3provided by RGD
    Official Full Name
    eukaryotic translation initiation factor 4E family member 3provided by RGD
    Primary source
    RGD:1586185
    See related
    EnsemblRapid:ENSRNOG00000010301 AllianceGenome:RGD:1586185
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable RNA 7-methylguanosine cap binding activity and translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be part of eukaryotic translation initiation factor 4F complex. Orthologous to human EIF4E3 (eukaryotic translation initiation factor 4E family member 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 111.4), Heart (RPKM 81.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Eif4e3 in Genome Data Viewer
    Location:
    4q34
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (133709802..133858398, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (132258502..132301808, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (132068581..132111092, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene forkhead box P1 Neighboring gene uncharacterized LOC134486619 Neighboring gene small nucleolar RNA U3 Neighboring gene uncharacterized LOC102555037 Neighboring gene immediate early response 3 interacting protein 1, pseudogene 1 Neighboring gene G protein-coupled receptor 27

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in regulation of translation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    eukaryotic translation initiation factor 4E type 3
    Names
    eukaryotic translation initiation factor 4E member 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106612.1 → NP_001100082.1  eukaryotic translation initiation factor 4E type 3

      See identical proteins and their annotated locations for NP_001100082.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473957
      UniProtKB/TrEMBL
      A0A8I6AF02, A6IBG8, B5DF58, F7F2U2
      Conserved Domains (1) summary
      pfam01652
      Location:34 → 181
      IF4E; Eukaryotic initiation factor 4E

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      133709802..133858398 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063285846.1 → XP_063141916.1  eukaryotic translation initiation factor 4E type 3 isoform X1

    2. XM_063285847.1 → XP_063141917.1  eukaryotic translation initiation factor 4E type 3 isoform X2

    RNA

    1. XR_010065627.1 RNA Sequence

      Related
      ENSRNOT00000097343.2
    Nucleotide Protein Strain
    Heading Accession and Version

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