Cmtm3 CKLF-like MARVEL transmembrane domain containing 3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Cmtm3provided by RGD
Official Full Name: CKLF-like MARVEL transmembrane domain containing 3provided by RGD
Primary source: RGD:1308763
See related: EnsemblRapid:ENSRNOG00000010691 AllianceGenome:RGD:1308763
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Cklfsf3
Summary: Predicted to act upstream of or within blastocyst hatching and positive regulation of B cell receptor signaling pathway. Predicted to be located in cytoplasmic vesicle; cytosol; and nuclear membrane. Predicted to be active in membrane. Orthologous to human CMTM3 (CKLF like MARVEL transmembrane domain containing 3). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Thymus (RPKM 106.3), Lung (RPKM 96.6) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 19p14

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	19	NC_086037.1 (629000..637152, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	19	NC_051354.1 (622563..630721, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	19	NC_005118.4 (830874..838528, complement)

Chromosome 19 - NC_086037.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

CMTM3 deficiency induces cardiac hypertrophy by regulating MAPK/ERK signaling.
Title: CMTM3 deficiency induces cardiac hypertrophy by regulating MAPK/ERK signaling.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
acts_upstream_of_or_within blastocyst hatching	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of B cell receptor signaling pathway	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in cytoplasmic vesicle	ISO Inferred from Sequence Orthology more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in nuclear membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: CKLF-like MARVEL transmembrane domain-containing protein 3

Names: chemokine-like factor super family 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.