U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    FSBP fibrinogen silencer binding protein [ Homo sapiens (human) ]

    Gene ID: 100861412, updated on 10-Dec-2024

    Summary

    Official Symbol
    FSBPprovided by HGNC
    Official Full Name
    fibrinogen silencer binding proteinprovided by HGNC
    Primary source
    HGNC:HGNC:43653
    See related
    Ensembl:ENSG00000265817 MIM:616306; AllianceGenome:HGNC:43653
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    Enables identical protein binding activity. Located in nucleoplasm. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in testis (RPKM 1.6), prostate (RPKM 1.4) and 25 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See FSBP in Genome Data Viewer
    Location:
    8q22.1
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (94427716..94436944, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (95552557..95561784, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (95439944..95449172, complement)

    Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107986896 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr8:95319922-95321121 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr8:95353266-95353915 Neighboring gene ribosomal protein S4X pseudogene 10 Neighboring gene RAD54 homolog B Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr8:95447028-95447528 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27630 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19366 Neighboring gene NANOG hESC enhancer GRCh37_chr8:95456748-95457280 Neighboring gene H3K27ac hESC enhancer GRCh37_chr8:95480258-95480884 Neighboring gene H3K27ac hESC enhancer GRCh37_chr8:95480885-95481510 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19367 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27631 Neighboring gene vir like m6A methyltransferase associated Neighboring gene H3K27ac hESC enhancer GRCh37_chr8:95546863-95547362 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27632 Neighboring gene ribosomal protein L31 pseudogene Neighboring gene VIRMA divergent transcript

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ23692

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    fibrinogen silencer-binding protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001256141.2NP_001243070.1  fibrinogen silencer-binding protein

      See identical proteins and their annotated locations for NP_001243070.1

      Status: VALIDATED

      Source sequence(s)
      AC023632, AF007866, AK074272
      Consensus CDS
      CCDS59106.1
      UniProtKB/Swiss-Prot
      O95073, Q8N4S5
      Related
      ENSP00000420405.2, ENST00000481490.3
      Conserved Domains (1) summary
      pfam13873
      Location:685
      Myb_DNA-bind_5; Myb/SANT-like DNA-binding domain

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

      Range
      94427716..94436944 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060932.1 Alternate T2T-CHM13v2.0

      Range
      95552557..95561784 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)