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    RING1B RING 1B [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839413, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RING1B
    Official Full Name
    RING 1B
    Primary source
    TAIR:AT1G03770
    Locus tag
    AT1G03770
    See related
    Araport:AT1G03770
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA RING 1B; ATRING1B; F21M11.32; F21M11_32; RING 1B
    Summary
    Encodes a nuclear localized protein with similarity to animal polycomb repressive core complex1 (PRC1) core component RING.Appears to function redundantly with ATRING1a, a close paralog. Both interact physically with CLF and LHP1 and appear to function together to repress class I KNOX gene expression.
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    Genomic context

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    See RING1B in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    9
    Sequence:
    Chromosome: 1; NC_003070.9 (944572..947682)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene switch 2 Neighboring gene Prefoldin chaperone subunit family protein Neighboring gene targeting protein for XKLP2 Neighboring gene Zinc finger C-x8-C-x5-C-x3-H type family protein Neighboring gene ERF domain protein 10

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Polycomb proteins RING1A/B promote H2A monoubiquitination to regulate female gametophyte development in Arabidopsis. Lv Y, et al. J Exp Bot, 2024 Aug 28. PMID 38717070
    2. The Arabidopsis PRC1-like ring-finger proteins are necessary for repression of embryonic traits during vegetative growth. Chen D, et al. Cell Res, 2010 Dec. PMID 21060339
    3. The Arabidopsis Nodulin Homeobox Factor AtNDX Interacts with AtRING1A/B and Negatively Regulates Abscisic Acid Signaling. Zhu Y, et al. Plant Cell, 2020 Mar. PMID 31919300, Free PMC Article
    4. Polycomb silencing of KNOX genes confines shoot stem cell niches in Arabidopsis. Xu L, et al. Curr Biol, 2008 Dec 23. PMID 19097900
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Polycomb proteins RING1A/B promote H2A monoubiquitination to regulate female gametophyte development in Arabidopsis.
      Title: Polycomb proteins RING1A/B promote H2A monoubiquitination to regulate female gametophyte development in Arabidopsis.
    2. The Arabidopsis Nodulin Homeobox Factor AtNDX Interacts with AtRING1A/B and Negatively Regulates Abscisic Acid Signaling.
      Title: The Arabidopsis Nodulin Homeobox Factor AtNDX Interacts with AtRING1A/B and Negatively Regulates Abscisic Acid Signaling.
    3. AtRING1b is elevated in the Atbmi1a Atbmi1b mutant, suggesting a self-regulatory feedback mechanism.
      Title: The Arabidopsis PRC1-like ring-finger proteins are necessary for repression of embryonic traits during vegetative growth.
    Submit: New GeneRIF Correction

    General gene information

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    NM_001331440.1
    NM_001331441.1
    NM_100256.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell fate determination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in maintenance of floral meristem identity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in maintenance of inflorescence meristem identity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in maintenance of shoot apical meristem identity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of DNA-templated transcription IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of gene expression, epigenetic IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of PRC1 complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    RING 1B
    NP_001184901.1
    • RING 1B (RING1B); FUNCTIONS IN: zinc ion binding; INVOLVED IN: negative regulation of gene expression, epigenetic; LOCATED IN: nucleus, PRC1 complex; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type, conserved site (InterPro:IPR017907), Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, C3HC4 RING-type (InterPro:IPR018957); BEST Arabidopsis thaliana protein match is: RING 1A (TAIR:AT5G44280.1).
    NP_001318915.1
    • RING 1B (RING1B); FUNCTIONS IN: zinc ion binding; INVOLVED IN: negative regulation of gene expression, epigenetic; LOCATED IN: nucleus, PRC1 complex; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type, conserved site (InterPro:IPR017907), Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, C3HC4 RING-type (InterPro:IPR018957); BEST Arabidopsis thaliana protein match is: RING 1A (TAIR:AT5G44280.1).
    NP_171873.2
    • RING 1B (RING1B); FUNCTIONS IN: zinc ion binding; INVOLVED IN: negative regulation of gene expression, epigenetic; LOCATED IN: nucleus, PRC1 complex; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type, conserved site (InterPro:IPR017907), Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, C3HC4 RING-type (InterPro:IPR018957); BEST Arabidopsis thaliana protein match is: RING 1A (TAIR:AT5G44280.1); Has 7001 Blast hits to 4383 proteins in 552 species: Archae - 10; Bacteria - 208; Metazoa - 3701; Fungi - 387; Plants - 512; Viruses - 317; Other Eukaryotes - 1866 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      944572..947682
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001197972.1 → NP_001184901.1  RING 1B [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001184901.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9SGG5, F4I2H4
      Conserved Domains (1) summary
      cd00162
      Location:104 → 148
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

    2. NM_001331439.1 → NP_001323369.1  RING 1B [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AWT6, A0A7G2DU14

    3. NM_001331438.1 → NP_001318915.1  RING 1B [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WM67, A0A5S9SGG5, F4I2H5
      Conserved Domains (1) summary
      cd16531
      Location:105 → 145
      RING-HC_RING1_like; RING finger, HC subclass, found in really interesting new gene proteins RING1, RING2 and similar proteins

    4. NM_100256.3 → NP_171873.2  RING 1B [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_171873.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WX00, Q9ZW99
      UniProtKB/TrEMBL
      A0A178WM72, A0A5S9SGG5
      Conserved Domains (1) summary
      cd00162
      Location:102 → 146
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

    5. NM_001331440.1 → NP_001323368.1  RING 1B [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AWX4

    6. NM_001331441.1 → NP_001323367.1  RING 1B [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AWT6, A0A7G2DU14
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0WX00.1

    Gene LinkOut

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