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    DL1C DYNAMIN-like 1C [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838048, updated on 18-Sep-2024

    Summary

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    Official Symbol
    DL1C
    Official Full Name
    DYNAMIN-like 1C
    Primary source
    TAIR:AT1G14830
    Locus tag
    AT1G14830
    See related
    Araport:AT1G14830
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ADL1C; ADL5; ARABIDOPSIS DYNAMIN-LIKE PROTEIN 5; DRP1C; DYNAMIN RELATED PROTEIN 1C; DYNAMIN-like 1C; DYNAMIN-LIKE PROTEIN 5; F10B6.23; F10B6_23
    Summary
    Encodes a dynamin-like protein that is involved in mitochondrial morphogenesis and pollen development. Protein is localized as speckles in the cytoplasm, partially co-localizes with mitochondrial markers, cell plate of dividing cells, and the tip of root hairs, root cap cells, and expanding part of trichoblasts.
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    Genomic context

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    See DL1C in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    16
    Sequence:
    Chromosome: 1; NC_003070.9 (5107416..5111746, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene semialdehyde dehydrogenase family protein Neighboring gene ncRNA Neighboring gene Sec14p-like phosphatidylinositol transfer family protein Neighboring gene microtubule-associated proteins 70-4 Neighboring gene nucleoporin 155 Neighboring gene nudix hydrolase homolog 18

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dynamics of Arabidopsis dynamin-related protein 1C and a clathrin light chain at the plasma membrane. Konopka CA, et al. Plant Cell, 2008 May. PMID 18502847, Free PMC Article
    2. The Arabidopsis dynamin-like proteins ADL1C and ADL1E play a critical role in mitochondrial morphogenesis. Jin JB, et al. Plant Cell, 2003 Oct. PMID 14523248, Free PMC Article
    3. The dynamin-like protein ADL1C is essential for plasma membrane maintenance during pollen maturation. Kang BH, et al. Plant J, 2003 Jul. PMID 12834397
    4. Comparison of the dynamics and functional redundancy of the Arabidopsis dynamin-related isoforms DRP1A and DRP1C during plant development. Konopka CA, et al. Plant Physiol, 2008 Aug. PMID 18344418, Free PMC Article
    5. Interactome of the plant-specific ESCRT-III component AtVPS2.2 in Arabidopsis thaliana. Ibl V, et al. J Proteome Res, 2012 Jan 1. PMID 22010978, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_101352.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within mitochondrial fission IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within mitochondrion organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within pollen maturation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in pollen maturation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell cortex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cell plate IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in clathrin-coated vesicle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in extracellular region HDA PubMed 
    NOT located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane HDA PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasmodesma HDA PubMed 

    General protein information

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    Preferred Names
    DYNAMIN-like 1C
    NP_172936.1
    • DYNAMIN-like 1C (DL1C); FUNCTIONS IN: GTP binding, GTPase activity; INVOLVED IN: mitochondrial fission, pollen maturation, mitochondrion organization; LOCATED IN: cell cortex, plasma membrane, membrane, cell plate; EXPRESSED IN: 29 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Dynamin GTPase effector (InterPro:IPR003130), Dynamin, GTPase domain (InterPro:IPR001401), Dynamin, GTPase region, conserved site (InterPro:IPR019762), GTPase effector domain, GED (InterPro:IPR020850), Dynamin central region (InterPro:IPR000375); BEST Arabidopsis thaliana protein match is: DYNAMIN-like 1E (TAIR:AT3G60190.1); Has 2810 Blast hits to 2715 proteins in 313 species: Archae - 2; Bacteria - 34; Metazoa - 1054; Fungi - 805; Plants - 579; Viruses - 0; Other Eukaryotes - 336 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      5107416..5111746 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101352.3 → NP_172936.1  DYNAMIN-like 1C [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_172936.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LF21, Q8S3C8, Q9FNX6, Q9LQU8, Q9SE81
      UniProtKB/TrEMBL
      A0A178W4V6, A0A5S9UG06
      Conserved Domains (3) summary
      cd08771
      Location:35 → 301
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
      pfam01031
      Location:224 → 488
      Dynamin_M; Dynamin central region
      pfam02212
      Location:522 → 611
      GED; Dynamin GTPase effector domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8LF21.2

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