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    MBD11 methyl-CPG-binding domain 11 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820822, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MBD11
    Official Full Name
    methyl-CPG-binding domain 11
    Primary source
    TAIR:AT3G15790
    Locus tag
    AT3G15790
    See related
    Araport:AT3G15790
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATMBD11; methyl-CPG-binding domain 11
    Summary
    Protein containing methyl-CpG-binding domain.Has sequence similarity to human MBD proteins.
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    Genomic context

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    See MBD11 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    4
    Sequence:
    Chromosome: 3; NC_003074.8 (5342712..5344715)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Glycosyl hydrolase superfamily protein Neighboring gene LURP-one-like protein (DUF567)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Ten members of the Arabidopsis gene family encoding methyl-CpG-binding domain proteins are transcriptionally active and at least one, AtMBD11, is crucial for normal development. Berg A, et al. Nucleic Acids Res, 2003 Sep 15. PMID 12954765, Free PMC Article
    2. Characterization of Arabidopsis thaliana methyl-CpG-binding domain (MBD) proteins. Zemach A, et al. Plant J, 2003 Jun. PMID 12787239
    3. An abscisic acid-responsive protein interaction network for sucrose non-fermenting related kinase1 in abiotic stress response. Carianopol CS, et al. Commun Biol, 2020 Mar 26. PMID 32218501, Free PMC Article
    4. CrY2H-seq: a massively multiplexed assay for deep-coverage interactome mapping. Wanamaker SA, et al. Nat Methods, 2017 Aug. PMID 28650476, Free PMC Article
    5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001338188.1
    NM_001338189.1
    NM_112449.6

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables methyl-CpG binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    methyl-CPG-binding domain 11
    NP_001319562.1
    • methyl-CPG-binding domain 11 (MBD11); FUNCTIONS IN: methyl-CpG binding, DNA binding; INVOLVED IN: biological_process unknown; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA-binding, integrase-type (InterPro:IPR016177), Methyl-CpG DNA binding (InterPro:IPR001739); BEST Arabidopsis thaliana protein match is: methyl-CPG-binding domain 10 (TAIR:AT1G15340.1); Has 9357 Blast hits to 6006 proteins in 613 species: Archae - 14; Bacteria - 964; Metazoa - 3510; Fungi - 943; Plants - 531; Viruses - 98; Other Eukaryotes - 3297 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      5342712..5344715
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001338188.1 → NP_001319562.1  methyl-CPG-binding domain 11 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WUS8, Q9LW00
      UniProtKB/TrEMBL
      A0A178VFI4, A0A5S9XCQ1
      Conserved Domains (1) summary
      cl00110
      Location:13 → 78
      MBD; MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...

    2. NM_112449.6 → NP_188200.1  methyl-CPG-binding domain 11 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_188200.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WUS8, Q9LW00
      UniProtKB/TrEMBL
      A0A178VFI4, A0A5S9XCQ1
      Conserved Domains (1) summary
      cl00110
      Location:13 → 78
      MBD; MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...

    3. NM_001338189.1 → NP_001326173.1  methyl-CPG-binding domain 11 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WUS8, Q9LW00
      UniProtKB/TrEMBL
      A0A178VFI4, A0A5S9XCQ1
      Conserved Domains (1) summary
      cl00110
      Location:13 → 78
      MBD; MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LW00.1

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