Mcmbp minichromosome maintenance complex binding protein [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Mcmbpprovided by MGI
Official Full Name: minichromosome maintenance complex binding proteinprovided by MGI
Primary source: MGI:MGI:1920977
See related: Ensembl:ENSMUSG00000048170 AllianceGenome:MGI:1920977
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: MCM-BP; 1110007A13Rik
Summary: Predicted to enable chromatin binding activity. Predicted to be involved in DNA-templated DNA replication and sister chromatid cohesion. Predicted to be located in cell junction; cytosol; and nucleoplasm. Predicted to be part of MCM complex. Orthologous to human MCMBP (minichromosome maintenance complex binding protein). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Ubiquitous expression in CNS E11.5 (RPKM 21.9), thymus adult (RPKM 17.2) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 7 F3; 7 70.41 cM

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (128298165..128342153, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (128696441..128740429, complement)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (3)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

NoName (e-PCR)
- UniSTS:235788

RH126929 (e-PCR)
- UniSTS:208212

RH118312 (e-PCR)
- UniSTS:123536

AU017382 (e-PCR)
- UniSTS:159700

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables chromatin binding	IBA Inferred from Biological aspect of Ancestor more info
enables chromatin binding	ISO Inferred from Sequence Orthology more info
enables chromatin binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in DNA-templated DNA replication	IBA Inferred from Biological aspect of Ancestor more info
involved_in DNA-templated DNA replication	ISO Inferred from Sequence Orthology more info
involved_in DNA-templated DNA replication	ISS Inferred from Sequence or Structural Similarity more info
involved_in cell division	IEA Inferred from Electronic Annotation more info
involved_in sister chromatid cohesion	ISO Inferred from Sequence Orthology more info
involved_in sister chromatid cohesion	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
part_of MCM complex	ISO Inferred from Sequence Orthology more info
part_of MCM complex	ISS Inferred from Sequence or Structural Similarity more info
located_in cell junction	ISO Inferred from Sequence Orthology more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: mini-chromosome maintenance complex-binding protein

Names: MCM (minichromosome maintenance deficient) binding protein; MCM-binding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.