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    Y67D8C.9 Aminopeptidase [ Caenorhabditis elegans ]

    Gene ID: 177088, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y67D8C.9
    Official Full Name
    Aminopeptidase
    Primary source
    WormBase:WBGene00022073
    Locus tag
    CELE_Y67D8C.9
    See related
    AllianceGenome:WB:WBGene00022073
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable metalloaminopeptidase activity; peptide binding activity; and zinc ion binding activity. Involved in embryo development; regulation of egg-laying behavior; and regulation of meiotic cell cycle process involved in oocyte maturation. Predicted to be active in cytoplasm; extracellular space; and membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y67D8C.9 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    14
    Sequence:
    Chromosome: IV; NC_003282.8 (3077466..3086925, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene G_PROTEIN_RECEP_F1_2 domain-containing protein;LMBR1-like membrane protein Neighboring gene Chondroitin proteoglycan 9 Neighboring gene LisH domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Calcium-transporting ATPase Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Collaboration within the M1 aminopeptidase family promotes reproductive success in Caenorhabditis elegans. Althoff MJ, et al. Dev Genes Evol, 2014 Jun. PMID 24663498
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables aminopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metalloaminopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metallopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables peptide binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables zinc ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in embryo development ending in birth or egg hatching IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in peptide catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of egg-laying behavior IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in regulation of meiotic cell cycle process involved in oocyte maturation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in regulation of meiotic cell cycle process involved in oocyte maturation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Aminopeptidase
    NP_001122825.1
    • Confirmed by transcript evidence
    NP_001122826.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      3077466..3086925 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001129354.3 → NP_001122826.1  Aminopeptidase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001122826.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2L0M5
      Conserved Domains (2) summary
      cd09601
      Location:190 → 652
      M1_APN_2; Peptidase M1 Aminopeptidase N family incudes tricorn interacting factor F3, Endoplasmic reticulum aminopeptidase 1 (ERAP1), Aminopeptidase Q (APQ)
      pfam01433
      Location:182 → 584
      Peptidase_M1; Peptidase family M1

    2. NM_001129353.4 → NP_001122825.1  Aminopeptidase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001122825.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8W765
      Conserved Domains (2) summary
      cd09601
      Location:133 → 595
      M1_APN_2; Peptidase M1 Aminopeptidase N family incudes tricorn interacting factor F3, Endoplasmic reticulum aminopeptidase 1 (ERAP1), Aminopeptidase Q (APQ)
      pfam01433
      Location:125 → 527
      Peptidase_M1; Peptidase family M1
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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