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    • Showing Current items.

    F44B9.8 putative replication factor C subunit 5 [ Caenorhabditis elegans ]

    Gene ID: 176131, updated on 4-Jan-2025

    Summary

    Official Symbol
    F44B9.8
    Official Full Name
    putative replication factor C subunit 5
    Primary source
    WormBase:WBGene00018409
    Locus tag
    CELE_F44B9.8
    See related
    AllianceGenome:WB:WBGene00018409
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable ATP binding activity; ATP hydrolysis activity; and DNA binding activity. Predicted to contribute to DNA clamp loader activity. Predicted to be involved in DNA repair and DNA-templated DNA replication. Predicted to be part of DNA replication factor C complex. Predicted to be active in nucleus. Orthologous to human RFC5 (replication factor C subunit 5). [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

    See F44B9.8 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    5
    Sequence:
    Chromosome: III; NC_003281.10 (8028133..8029649, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene Glutamine/asparagine-rich protein mdt-30 Neighboring gene Uncharacterized protein Neighboring gene Phospholipase A2

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to DNA clamp loader activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in DNA repair IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in DNA replication IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in DNA-templated DNA replication IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of DNA replication factor C complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    putative replication factor C subunit 5
    NP_498750.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      8028133..8029649 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066349.8NP_498750.2  putative replication factor C subunit 5 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498750.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P34429, Q8ST15
      Conserved Domains (3) summary
      cd00009
      Location:44194
      AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
      PRK00440
      Location:27340
      rfc; replication factor C small subunit; Reviewed
      pfam08542
      Location:278340
      Rep_fac_C; Replication factor C C-terminal domain