IQCA1L IQ motif containing with AAA domain 1 like [Homo sapiens (human)] - Gene

Summary

Official Symbol: IQCA1Lprovided by HGNC
Official Full Name: IQ motif containing with AAA domain 1 likeprovided by HGNC
Primary source: HGNC:HGNC:22831
See related: Ensembl:ENSG00000278685 AllianceGenome:HGNC:22831
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: IQCA1P1
Summary: Predicted to enable ATP hydrolysis activity and microtubule severing ATPase activity. Predicted to be involved in microtubule cytoskeleton organization. [provided by Alliance of Genome Resources, Dec 2024]
Expression: Restricted expression toward testis (RPKM 1.5) See more
Orthologs: mouse all
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Genomic context

Location:: 7q36.1

Exon count:: 19

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	7	NC_000007.14 (151190873..151205496, complement)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	7	NC_060931.1 (152363965..152378590, complement)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	7	NC_000007.13 (150887960..150902582, complement)

Chromosome 7 - NC_000007.14 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Tissue-specific circular RNA induction during human fetal development
Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
BioProject: PRJNA270632
Publication: PMID 26076956
Analysis date: Mon Apr 2 22:54:59 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IBA Inferred from Biological aspect of Ancestor more info
enables microtubule severing ATPase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in microtubule cytoskeleton organization	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: IQ and AAA domain-containing protein 1-like

Names: IQ and AAA domain-containing protein 1 pseudogene 1; IQ motif containing with AAA domain 1-like protein; putative IQ and AAA domain-containing protein 1 pseudogene 1; putative IQ and AAA domain-containing protein 1-like; putative IQ motif containing with AAA domain 1 pseudogene 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001304419.2 → NP_001291348.1 IQ and AAA domain-containing protein 1-like

Status: VALIDATED

Source sequence(s)

AC010973, AL045644, AW444952, DN831123, DV080513, DY654655, HM370405, KF459644

Consensus CDS

CCDS78288.1

UniProtKB/Swiss-Prot

A0A087WYV2, A6NCM1

Related

ENSP00000482119.1, ENST00000615129.4

Conserved Domains (1) summary

COG0464
Location:561 → 734

SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]