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    Svopl SV2 related protein homolog (rat)-like [ Mus musculus (house mouse) ]

    Gene ID: 320590, updated on 4-Jan-2025

    Summary

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    Official Symbol
    Svoplprovided by MGI
    Official Full Name
    SV2 related protein homolog (rat)-likeprovided by MGI
    Primary source
    MGI:MGI:2444335
    See related
    Ensembl:ENSMUSG00000029830 AllianceGenome:MGI:2444335
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    9430071P14Rik
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Is expressed in genitourinary system and nose. Orthologous to human SVOPL (SVOP like). [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Biased expression in kidney adult (RPKM 1.9), genital fat pad adult (RPKM 0.7) and 10 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Svopl in Genome Data Viewer
    Location:
    6 B1; 6 17.34 cM
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (37960674..38023944, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (37983739..38047009, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer mm9_chr6:37820554-37820855 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:37821510-37821693 Neighboring gene general transcription factor IIB pseudogene Neighboring gene STARR-seq mESC enhancer starr_15610 Neighboring gene tripartite motif-containing 24 Neighboring gene STARR-positive B cell enhancer mm9_chr6:37846121-37846422 Neighboring gene STARR-seq mESC enhancer starr_15611 Neighboring gene STARR-seq mESC enhancer starr_15612 Neighboring gene vomeronasal 2, receptor 121 pseudogene Neighboring gene predicted gene, 33494 Neighboring gene ATPase, H+ transporting, lysosomal V0 subunit A4 Neighboring gene predicted gene, 57763 Neighboring gene transmembrane protein 213

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Identification of six putative human transporters with structural similarity to the drug transporter SLC22 family. Jacobsson JA, et al. Genomics, 2007 Nov. PMID 17714910
    2. Novel genes differentially expressed in cortical regions during late neurogenesis. Mühlfriedel S, et al. Eur J Neurosci, 2007 Jul. PMID 17614941
    3. Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. Gerber SD, et al. PLoS One, 2012. PMID 22432025, Free PMC Article
    4. Expression of metanephric nephron-patterning genes in differentiating mesonephric tubules. Georgas KM, et al. Dev Dyn, 2011 Jun. PMID 21491542, Free PMC Article
    5. Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment. Georgas K, et al. Dev Biol, 2009 Aug 15. PMID 19501082

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative transporter SVOPL
    Names
    SVOP-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177200.4 → NP_796174.2  putative transporter SVOPL

      Status: VALIDATED

      Source sequence(s)
      BB627230, BC058741
      Consensus CDS
      CCDS20009.2
      UniProtKB/Swiss-Prot
      Q6PDF3, Q8BM44
      Related
      ENSMUSP00000093743.5, ENSMUST00000096040.11
      Conserved Domains (2) summary
      cd06174
      Location:51 → 482
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00895
      Location:34 → 456
      2A0115; benzoate transport

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      37960674..38023944 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011241386.4 → XP_011239688.1  putative transporter SVOPL isoform X1

      Conserved Domains (1) summary
      cd17442
      Location:49 → 482
      MFS_SVOPL; Synaptic vesicle 2 (SV2)-related protein-like (SVOPL) of the Major Facilitator Superfamily

    2. XM_017321644.2 → XP_017177133.1  putative transporter SVOPL isoform X2

      Conserved Domains (1) summary
      cl28910
      Location:49 → 225
      MFS; Major Facilitator Superfamily
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6PDF3.1 GenPept UniProtKB/Swiss-Prot:Q6PDF3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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