Faxc failed axon connections homolog, metaxin like GST domain containing [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Faxcprovided by RGD
Official Full Name: failed axon connections homolog, metaxin like GST domain containingprovided by RGD
Primary source: RGD:1562449
See related: EnsemblRapid:ENSRNOG00000010106 AllianceGenome:RGD:1562449
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1562449
Summary: Predicted to be located in membrane. Predicted to be active in cytoplasm. Orthologous to human FAXC (failed axon connections homolog, metaxin like GST domain containing). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Brain (RPKM 85.6), Uterus (RPKM 20.0) and 2 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 5q21

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	5	NC_086023.1 (40277167..40336503)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	5	NC_051340.1 (35480137..35539741)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	5	NC_005104.4 (36076565..36135884)

Chromosome 5 - NC_086023.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: failed axon connections homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001271065.1 → NP_001257994.1 failed axon connections homolog

See identical proteins and their annotated locations for NP_001257994.1

Status: PROVISIONAL

Source sequence(s)

JAXUCZ010000005

UniProtKB/Swiss-Prot

D3ZAT9

Related

ENSRNOP00000104533.1, ENSRNOT00000127046.1

Conserved Domains (2) summary

pfam17171
Location:263 → 326

GST_C_6; Glutathione S-transferase, C-terminal domain

pfam17172
Location:117 → 212

GST_N_4; Glutathione S-transferase N-terminal domain