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    mrpl9 mitochondrial ribosomal protein L9 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 310653, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mrpl9provided by RGD
    Official Full Name
    mitochondrial ribosomal protein L9provided by RGD
    Primary source
    RGD:1359171
    See related
    EnsemblRapid:ENSRNOG00000020869 AllianceGenome:RGD:1359171
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Predicted to be active in mitochondrion. Orthologous to human MRPL9 (mitochondrial ribosomal protein L9). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 253.7), Thymus (RPKM 244.9) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See mrpl9 in Genome Data Viewer
    Location:
    2q34
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (184768837..184775787)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (182082012..182086758)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (195684750..195689470)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene tudor and KH domain containing Neighboring gene cytochrome c, somatic-like Neighboring gene ornithine decarboxylase antizyme 3 Neighboring gene uncharacterized LOC102556390 Neighboring gene regulatory subunit of type II PKA R-subunit domain containing 1 Neighboring gene CUGBP, Elav-like family member 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria. Suzuki T, et al. J Biol Chem, 2001 Jun 15. PMID 11279069
    2. Structures of the human mitochondrial ribosome in native states of assembly. Brown A, et al. Nat Struct Mol Biol, 2017 Oct. PMID 28892042, Free PMC Article
    3. Structure of the large ribosomal subunit from human mitochondria. Brown A, et al. Science, 2014 Nov 7. PMID 25278503, Free PMC Article
    4. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Mootha VK, et al. Cell, 2003 Nov 26. PMID 14651853
    5. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC95263

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of mitochondrial large ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of mitochondrial large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of mitochondrial large ribosomal subunit ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    large ribosomal subunit protein bL9m
    Names
    39S ribosomal protein L9, mitochondrial
    L9mt
    MRP-L9

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001007696.1 → NP_001007697.1  large ribosomal subunit protein bL9m

      See identical proteins and their annotated locations for NP_001007697.1

      Status: PROVISIONAL

      Source sequence(s)
      BC082085
      UniProtKB/Swiss-Prot
      Q641X9
      UniProtKB/TrEMBL
      A0A8L2QGW3, A6K2R3
      Related
      ENSRNOP00000028316.6, ENSRNOT00000028316.7
      Conserved Domains (2) summary
      CHL00160
      Location:88 → 223
      rpl9; ribosomal protein L9; Provisional
      pfam01281
      Location:92 → 137
      Ribosomal_L9_N; Ribosomal protein L9, N-terminal domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      184768837..184775787
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063281869.1 → XP_063137939.1  large ribosomal subunit protein bL9m isoform X1

      UniProtKB/TrEMBL
      A0A8I6AIX2, A0A8L2QGW3

    2. XM_039102342.2 → XP_038958270.1  large ribosomal subunit protein bL9m isoform X2

      Conserved Domains (1) summary
      pfam01281
      Location:92 → 137
      Ribosomal_L9_N; Ribosomal protein L9, N-terminal domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q641X9.1 GenPept UniProtKB/Swiss-Prot:Q641X9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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