Cib3 calcium and integrin binding family member 3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Cib3provided by RGD
Official Full Name: calcium and integrin binding family member 3provided by RGD
Primary source: RGD:1590245
See related: EnsemblRapid:ENSRNOG00000014600 AllianceGenome:RGD:1590245
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable calcium ion binding activity and magnesium ion binding activity. Predicted to be involved in calcium ion homeostasis. Orthologous to human CIB3 (calcium and integrin binding family member 3). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Spleen (RPKM 1.1), Thymus (RPKM 0.6) and 5 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 16p14

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	16	NC_086034.1 (17656453..17665848)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	16	NC_051351.1 (17622431..17631827)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	16	NC_005115.4 (19323516..19332830)

Chromosome 16 - NC_086034.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables calcium ion binding	IBA Inferred from Biological aspect of Ancestor more info
enables calcium ion binding	ISO Inferred from Sequence Orthology more info
enables magnesium ion binding	IBA Inferred from Biological aspect of Ancestor more info
enables magnesium ion binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in calcium ion homeostasis	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: calcium and integrin-binding family member 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001191081.2 → NP_001178010.1 calcium and integrin-binding family member 3

Status: VALIDATED

Source sequence(s)

JAXUCZ010000016

UniProtKB/TrEMBL

D4A189

Related

ENSRNOP00000019578.4, ENSRNOT00000019578.6

Conserved Domains (1) summary

COG5126
Location:6 → 178

FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]