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    HAND2-AS1 HAND2 antisense RNA 1 [ Homo sapiens (human) ]

    Gene ID: 79804, updated on 9-Dec-2024

    Summary

    Official Symbol
    HAND2-AS1provided by HGNC
    Official Full Name
    HAND2 antisense RNA 1provided by HGNC
    Primary source
    HGNC:HGNC:48872
    See related
    Ensembl:ENSG00000237125 MIM:617240; AllianceGenome:HGNC:48872
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    UPH; DEIN; NBLA00301
    Summary
    Predicted to be involved in positive regulation of gene expression. Predicted to act upstream of or within with a positive effect on cardiac right ventricle morphogenesis. Predicted to act upstream of or within transcription elongation by RNA polymerase II. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of chromatin. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in endometrium (RPKM 13.8), adrenal (RPKM 11.4) and 8 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See HAND2-AS1 in Genome Data Viewer
    Location:
    4q34.1
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (173528600..173591255)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (176868392..176930983)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (174449751..174512406)

    Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene stimulator of chondrogenesis 1 Neighboring gene uncharacterized LOC101928409 Neighboring gene uncharacterized LOC124900815 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr4:174439311-174440510 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:174445895-174446436 Neighboring gene uncharacterized LOC124900816 Neighboring gene NANOG hESC enhancer GRCh37_chr4:174457885-174458386 Neighboring gene heart and neural crest derivatives expressed 2 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:174529467-174530044 Neighboring gene mortality factor 4 (pseudogene) Neighboring gene RAN pseudogene 6

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Other Names

    • HAND2 antisense RNA 1 (head to head)
    • differentially expressed in neuroblastoma
    • neuroblastoma transcript 301

    Clone Names

    • FLJ11539, FLJ41674, FLJ50876

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_003679.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1)
      Source sequence(s)
      AA156933, EF529505
      Related
      ENST00000505621.6
    2. NR_136192.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2)
      Source sequence(s)
      AA156933, BQ882603, EU000853
      Related
      ENST00000507062.7
    3. NR_136193.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3)
      Source sequence(s)
      AA156933, AB075501, AC093849, BQ882603, EU000853
    4. NR_136194.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4)
      Source sequence(s)
      AA156933, AK300846, BQ882603, EU000853
    5. NR_136195.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5)
      Source sequence(s)
      AC093849, AC113154, AK054605, BQ882603
      Related
      ENST00000503474.5
    6. NR_136196.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6)
      Source sequence(s)
      AC079789, BQ882603, DA863153, DB292439
    7. NR_136197.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7)
      Source sequence(s)
      AA156933, DC421261, EU000853
    8. NR_136198.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8)
      Source sequence(s)
      AA156933, BG519698, BQ882603, EU000853
    9. NR_136199.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (9)
      Source sequence(s)
      AA156933, AC093849, BQ882603, DC386781, EU000853
    10. NR_136200.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (10)
      Source sequence(s)
      AA156933, AB075501, AU253586, BQ882603, EU000853
      Related
      ENST00000502896.6
    11. NR_136201.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (11)
      Source sequence(s)
      AA156933, AB075501, AC093849, BQ882603, DA665500, EU000853

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

      Range
      173528600..173591255
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060928.1 Alternate T2T-CHM13v2.0

      Range
      176868392..176930983
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)