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    SHPRH SNF2 histone linker PHD RING helicase [ Homo sapiens (human) ]

    Gene ID: 257218, updated on 10-Dec-2024

    Summary

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    Official Symbol
    SHPRHprovided by HGNC
    Official Full Name
    SNF2 histone linker PHD RING helicaseprovided by HGNC
    Primary source
    HGNC:HGNC:19336
    See related
    Ensembl:ENSG00000146414 MIM:608048; AllianceGenome:HGNC:19336
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    RAD5; bA545I5.2
    Summary
    SHPRH is a ubiquitously expressed protein that contains motifs characteristics of several DNA repair proteins, transcription factors, and helicases. SHPRH is a functional homolog of S. cerevisiae RAD5 (Unk et al., 2006 [PubMed 17108083]).[supplied by OMIM, Mar 2008]
    Expression
    Ubiquitous expression in ovary (RPKM 1.7), thyroid (RPKM 1.5) and 25 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See SHPRH in Genome Data Viewer
    Location:
    6q24.3
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (145857838..145964358, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (147050896..147157428, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (146205943..146285494, complement)

    Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene EPM2A divergent transcript Neighboring gene uncharacterized LOC124901419 Neighboring gene H3K27ac hESC enhancer GRCh37_chr6:146135340-146135894 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25227 Neighboring gene F-box protein 30 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25228 Neighboring gene uncharacterized LOC124901420 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25229 Neighboring gene H3K27ac hESC enhancer GRCh37_chr6:146285382-146286369 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:146350016-146350516 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:146350517-146351017 Neighboring gene glutamate metabotropic receptor 1 Neighboring gene FUN14 domain containing 2 pseudogene 3 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr6:146578666-146579217 Neighboring gene RNA, 5S ribosomal pseudogene 222

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Integrative genomics identifies SHPRH as a tumor suppressor gene in lung adenocarcinoma that regulates DNA damage response. Nagelberg AL, et al. Br J Cancer, 2024 Aug. PMID 38890444, Free PMC Article
    2. A peptide encoded by the circular form of the SHPRH gene induces apoptosis in neuroblastoma cells. Gao J, et al. PeerJ, 2024. PMID 38282862, Free PMC Article
    3. SHPRH as a new player in ribosomal RNA transcription and its potential role in homeostasis of ribosomal DNA repeats. Lee D, et al. Transcription, 2018. PMID 29139335, Free PMC Article
    4. Cloning and characterization of a novel gene, SHPRH, encoding a conserved putative protein with SNF2/helicase and PHD-finger domains from the 6q24 region. Sood R, et al. Genomics, 2003 Aug. PMID 12837266
    5. Human SHPRH suppresses genomic instability through proliferating cell nuclear antigen polyubiquitination. Motegi A, et al. J Cell Biol, 2006 Dec 4. PMID 17130289, Free PMC Article

    See all (53) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Integrative genomics identifies SHPRH as a tumor suppressor gene in lung adenocarcinoma that regulates DNA damage response.
      Title: Integrative genomics identifies SHPRH as a tumor suppressor gene in lung adenocarcinoma that regulates DNA damage response.
    2. A peptide encoded by the circular form of the SHPRH gene induces apoptosis in neuroblastoma cells.
      Title: A peptide encoded by the circular form of the SHPRH gene induces apoptosis in neuroblastoma cells.
    3. KMT2B promotes SHPRH expression to regulate (131)I sensitivity in thyroid carcinoma cells by affecting FYN protein stability.
      Title: KMT2B promotes SHPRH expression to regulate (131)I sensitivity in thyroid carcinoma cells by affecting FYN protein stability.
    4. The Human RAD5 Homologs, HLTF and SHPRH, Have Separate Functions in DNA Damage Tolerance Dependent on The DNA Lesion Type.
      Title: The Human RAD5 Homologs, HLTF and SHPRH, Have Separate Functions in DNA Damage Tolerance Dependent on The DNA Lesion Type.
    5. Helicase-Like Transcription Factor HLTF and E3 Ubiquitin Ligase SHPRH Confer DNA Damage Tolerance through Direct Interactions with Proliferating Cell Nuclear Antigen (PCNA).
      Title: Helicase-Like Transcription Factor HLTF and E3 Ubiquitin Ligase SHPRH Confer DNA Damage Tolerance through Direct Interactions with Proliferating Cell Nuclear Antigen (PCNA).
    6. circ-0001649 regulated behaviors of hepatocellular carcinoma cells by targeting SHPRH; circ-0001649 served as a ceRNA to sponge miR-127-5p, miR-612 and miR-4688, thus activating SHPRH
      Title: Circular RNA hsa_circ_0001649 inhibits hepatocellular carcinoma progression via multiple miRNAs sponge.
    7. A novel perspective regarding circRNA function in physiological and pathological processes: specifically, SHPRH-146aa generated from overlapping genetic codes of circ-SHPRH is a tumor suppressor in human glioblastoma.
      Title: A novel protein encoded by the circular form of the SHPRH gene suppresses glioma tumorigenesis.
    8. This study suggests that SHPRH could be a link between mTOR-mediated epigenetic regulations and rRNA transcription, while concomitantly affecting genomic integrity.
      Title: SHPRH as a new player in ribosomal RNA transcription and its potential role in homeostasis of ribosomal DNA repeats.
    9. evidence that SHPRH functions in rRNA transcription through its interaction with histone H3 in a mammalian target of rapamycin (mTOR)-dependent manner
      Title: SHPRH regulates rRNA transcription by recognizing the histone code in an mTOR-dependent manner.
    10. HLTF and SHPRH suppress mutagenesis in a damage-specific manner, preventing mutations induced by UV rays and methyl methanesulfonate.
      Title: SHPRH and HLTF act in a damage-specific manner to coordinate different forms of postreplication repair and prevent mutagenesis.
    Submit: New GeneRIF Correction See all GeneRIFs (15)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ27258, FLJ37625, FLJ45012, FLJ90837, KIAA2023, MGC134886

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ubiquitin protein ligase binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ubiquitin-protein transferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA damage response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within DNA damage response IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in nucleosome assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein polyubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein polyubiquitination IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein ubiquitination TAS
    Traceable Author Statement
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
    		  
    part_of nucleosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase SHPRH
    Names
    2610103K11Rik
    RING-type E3 ubiquitin transferase SHPRH
    SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
    SNF2, histone-linker, PHD and RING finger domain-containing helicase
    NP_001036148.2
    NP_001357256.1
    NP_001357257.1
    NP_775105.1
    XP_006715502.1
    XP_006715506.1
    XP_011534021.1
    XP_011534024.1
    XP_016866180.1
    XP_016866181.1
    XP_016866182.1
    XP_047274556.1
    XP_047274557.1
    XP_047274558.1
    XP_047274559.1
    XP_047274560.1
    XP_054211055.1
    XP_054211056.1
    XP_054211057.1
    XP_054211058.1
    XP_054211059.1
    XP_054211060.1
    XP_054211061.1
    XP_054211062.1
    XP_054211063.1
    XP_054211064.1
    XP_054211065.1
    XP_054211066.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001042683.3 → NP_001036148.2  E3 ubiquitin-protein ligase SHPRH isoform a

      See identical proteins and their annotated locations for NP_001036148.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).
      Source sequence(s)
      AA315737, AK126959, AL451145, AY161136, AY163808, BC117686, BX648322
      Consensus CDS
      CCDS43513.2
      UniProtKB/Swiss-Prot
      Q149N8, Q149N9, Q5VV79, Q68DS5, Q7Z5J5, Q8IVE8, Q8IWQ9, Q8N1S8, Q8NBR7
      UniProtKB/TrEMBL
      A0A0D9SFM0
      Related
      ENSP00000275233.7, ENST00000275233.12
      Conserved Domains (7) summary
      COG0553
      Location:24 → 389
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd15547
      Location:660 → 706
      PHD_SHPRH; PHD finger found in E3 ubiquitin-protein ligase SHPRH
      cd16569
      Location:1429 → 1479
      RING-HC_SHPRH; RING finger, HC subclass, found in SNF2 histone-linker PHD finger RING finger helicase (SHPRH) and similar proteins
      pfam00538
      Location:440 → 511
      Linker_histone; linker histone H1 and H5 family
      cd18793
      Location:1508 → 1633
      SF2_C_SNF; C-terminal helicase domain of the SNF family helicases
      cd18070
      Location:702 → 903
      DEXQc_SHPRH; DEXQ-box helicase domain of SHPRH
      cl28899
      Location:304 → 409
      DEAD-like_helicase_N; N-terminal helicase domain of the DEAD-box helicase superfamily

    2. NM_001370327.1 → NP_001357256.1  E3 ubiquitin-protein ligase SHPRH isoform a

      Status: VALIDATED

      Source sequence(s)
      AL356599, AL451145
      Consensus CDS
      CCDS43513.2
      UniProtKB/Swiss-Prot
      Q149N8, Q149N9, Q5VV79, Q68DS5, Q7Z5J5, Q8IVE8, Q8IWQ9, Q8N1S8, Q8NBR7
      UniProtKB/TrEMBL
      A0A0D9SFM0
      Related
      ENSP00000356475.2, ENST00000367505.6
      Conserved Domains (7) summary
      COG0553
      Location:24 → 389
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd15547
      Location:660 → 706
      PHD_SHPRH; PHD finger found in E3 ubiquitin-protein ligase SHPRH
      cd16569
      Location:1429 → 1479
      RING-HC_SHPRH; RING finger, HC subclass, found in SNF2 histone-linker PHD finger RING finger helicase (SHPRH) and similar proteins
      pfam00538
      Location:440 → 511
      Linker_histone; linker histone H1 and H5 family
      cd18793
      Location:1508 → 1633
      SF2_C_SNF; C-terminal helicase domain of the SNF family helicases
      cd18070
      Location:702 → 903
      DEXQc_SHPRH; DEXQ-box helicase domain of SHPRH
      cl28899
      Location:304 → 409
      DEAD-like_helicase_N; N-terminal helicase domain of the DEAD-box helicase superfamily

    3. NM_001370328.1 → NP_001357257.1  E3 ubiquitin-protein ligase SHPRH isoform c

      Status: VALIDATED

      Source sequence(s)
      AL356599, AL451145
      Conserved Domains (4) summary
      cd15547
      Location:179 → 225
      PHD_SHPRH; PHD finger found in E3 ubiquitin-protein ligase SHPRH
      cd16569
      Location:948 → 998
      RING-HC_SHPRH; RING finger, HC subclass, found in SNF2 histone-linker PHD finger RING finger helicase (SHPRH) and similar proteins
      cd18793
      Location:1027 → 1152
      SF2_C_SNF; C-terminal helicase domain of the SNF family helicases
      cd18070
      Location:221 → 422
      DEXQc_SHPRH; DEXQ-box helicase domain of SHPRH

    4. NM_173082.4 → NP_775105.1  E3 ubiquitin-protein ligase SHPRH isoform b

      See identical proteins and their annotated locations for NP_775105.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses three alternate splice sites in the coding region, one of which results in a frameshift, compared to variant 1. It encodes isoform b, which is shorter and has a distinct C-terminus, compared to isoform a.
      Source sequence(s)
      AA315737, AL451145, AY161136, AY163808, BX648322
      Consensus CDS
      CCDS47496.1
      UniProtKB/TrEMBL
      A0A0D9SFM0
      Related
      ENSP00000412797.2, ENST00000438092.6
      Conserved Domains (7) summary
      COG0553
      Location:1515 → 1652
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd00162
      Location:1436 → 1486
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cd15547
      Location:660 → 706
      PHD_SHPRH; PHD finger found in E3 ubiquitin-protein ligase SHPRH
      pfam00176
      Location:716 → 987
      SNF2_N; SNF2 family N-terminal domain
      pfam00271
      Location:1517 → 1626
      Helicase_C; Helicase conserved C-terminal domain
      pfam00538
      Location:440 → 511
      Linker_histone; linker histone H1 and H5 family
      pfam13424
      Location:1029 → 1113
      TPR_12; Tetratricopeptide repeat

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

      Range
      145857838..145964358 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047418600.1 → XP_047274556.1  E3 ubiquitin-protein ligase SHPRH isoform X1

      UniProtKB/TrEMBL
      A0A0D9SFM0

    2. XM_006715439.5 → XP_006715502.1  E3 ubiquitin-protein ligase SHPRH isoform X3

      See identical proteins and their annotated locations for XP_006715502.1

      UniProtKB/TrEMBL
      A0A0D9SFM0
      Conserved Domains (7) summary
      COG0553
      Location:1511 → 1648
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd00162
      Location:1432 → 1482
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cd15547
      Location:660 → 706
      PHD_SHPRH; PHD finger found in E3 ubiquitin-protein ligase SHPRH
      pfam00176
      Location:716 → 987
      SNF2_N; SNF2 family N-terminal domain
      pfam00271
      Location:1513 → 1622
      Helicase_C; Helicase conserved C-terminal domain
      pfam00538
      Location:440 → 511
      Linker_histone; linker histone H1 and H5 family
      pfam13424
      Location:1020 → 1104
      TPR_12; Tetratricopeptide repeat

    3. XM_047418601.1 → XP_047274557.1  E3 ubiquitin-protein ligase SHPRH isoform X1

      UniProtKB/TrEMBL
      A0A0D9SFM0

    4. XM_006715443.5 → XP_006715506.1  E3 ubiquitin-protein ligase SHPRH isoform X7

      UniProtKB/TrEMBL
      A0A0D9SFM0
      Conserved Domains (5) summary
      cd00162
      Location:1432 → 1482
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cd15547
      Location:660 → 706
      PHD_SHPRH; PHD finger found in E3 ubiquitin-protein ligase SHPRH
      pfam00176
      Location:716 → 987
      SNF2_N; SNF2 family N-terminal domain
      pfam00538
      Location:440 → 511
      Linker_histone; linker histone H1 and H5 family
      pfam13424
      Location:1020 → 1104
      TPR_12; Tetratricopeptide repeat

    5. XM_047418603.1 → XP_047274559.1  E3 ubiquitin-protein ligase SHPRH isoform X7

      UniProtKB/TrEMBL
      A0A0D9SFM0

    6. XM_017010693.3 → XP_016866182.1  E3 ubiquitin-protein ligase SHPRH isoform X4

      UniProtKB/TrEMBL
      A0A0D9SFM0

    7. XM_017010691.3 → XP_016866180.1  E3 ubiquitin-protein ligase SHPRH isoform X2

      UniProtKB/TrEMBL
      A0A0D9SFM0

    8. XM_017010692.2 → XP_016866181.1  E3 ubiquitin-protein ligase SHPRH isoform X2

      UniProtKB/TrEMBL
      A0A0D9SFM0

    9. XM_011535719.4 → XP_011534021.1  E3 ubiquitin-protein ligase SHPRH isoform X5

      UniProtKB/TrEMBL
      A0A0D9SFM0
      Conserved Domains (7) summary
      COG0553
      Location:1511 → 1658
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd00162
      Location:1432 → 1482
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cd15547
      Location:660 → 706
      PHD_SHPRH; PHD finger found in E3 ubiquitin-protein ligase SHPRH
      pfam00176
      Location:716 → 987
      SNF2_N; SNF2 family N-terminal domain
      pfam00271
      Location:1513 → 1622
      Helicase_C; Helicase conserved C-terminal domain
      pfam00538
      Location:440 → 511
      Linker_histone; linker histone H1 and H5 family
      pfam13424
      Location:1020 → 1104
      TPR_12; Tetratricopeptide repeat

    10. XM_047418602.1 → XP_047274558.1  E3 ubiquitin-protein ligase SHPRH isoform X6

      UniProtKB/TrEMBL
      A0A0D9SFM0

    11. XM_047418604.1 → XP_047274560.1  E3 ubiquitin-protein ligase SHPRH isoform X8

      Related
      ENSP00000430528.1, ENST00000519632.5

    12. XM_011535722.4 → XP_011534024.1  E3 ubiquitin-protein ligase SHPRH isoform X9

      Conserved Domains (3) summary
      COG0553
      Location:24 → 389
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd15547
      Location:660 → 706
      PHD_SHPRH; PHD finger found in E3 ubiquitin-protein ligase SHPRH
      pfam00538
      Location:440 → 511
      Linker_histone; linker histone H1 and H5 family

    RNA

    1. XR_942393.4 RNA Sequence

    2. XR_942390.4 RNA Sequence

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060930.1 Alternate T2T-CHM13v2.0

      Range
      147050896..147157428 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054355080.1 → XP_054211055.1  E3 ubiquitin-protein ligase SHPRH isoform X1

      UniProtKB/TrEMBL
      A0A0D9SFM0

    2. XM_054355084.1 → XP_054211059.1  E3 ubiquitin-protein ligase SHPRH isoform X3

      UniProtKB/TrEMBL
      A0A0D9SFM0

    3. XM_054355081.1 → XP_054211056.1  E3 ubiquitin-protein ligase SHPRH isoform X1

      UniProtKB/TrEMBL
      A0A0D9SFM0

    4. XM_054355087.1 → XP_054211062.1  E3 ubiquitin-protein ligase SHPRH isoform X7

      UniProtKB/TrEMBL
      A0A0D9SFM0

    5. XM_054355088.1 → XP_054211063.1  E3 ubiquitin-protein ligase SHPRH isoform X7

      UniProtKB/TrEMBL
      A0A0D9SFM0

    6. XM_054355085.1 → XP_054211060.1  E3 ubiquitin-protein ligase SHPRH isoform X4

      UniProtKB/TrEMBL
      A0A0D9SFM0

    7. XM_054355082.1 → XP_054211057.1  E3 ubiquitin-protein ligase SHPRH isoform X2

      UniProtKB/TrEMBL
      A0A0D9SFM0

    8. XM_054355083.1 → XP_054211058.1  E3 ubiquitin-protein ligase SHPRH isoform X2

      UniProtKB/TrEMBL
      A0A0D9SFM0

    9. XM_054355086.1 → XP_054211061.1  E3 ubiquitin-protein ligase SHPRH isoform X5

      UniProtKB/TrEMBL
      A0A0D9SFM0

    10. XM_054355089.1 → XP_054211064.1  E3 ubiquitin-protein ligase SHPRH isoform X10

      UniProtKB/TrEMBL
      A0A0D9SFM0

    11. XM_054355090.1 → XP_054211065.1  E3 ubiquitin-protein ligase SHPRH isoform X8

    12. XM_054355091.1 → XP_054211066.1  E3 ubiquitin-protein ligase SHPRH isoform X9

    RNA

    1. XR_008487292.1 RNA Sequence

    2. XR_008487293.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q149N8.2 GenPept UniProtKB/Swiss-Prot:Q149N8

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