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    SC35 serine/arginine-rich splicing factor-like protein, putative [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836541, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SC35
    Official Full Name
    serine/arginine-rich splicing factor-like protein, putative
    Primary source
    TAIR:AT5G64200
    Locus tag
    AT5G64200
    See related
    Araport:AT5G64200
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA ORTHOLOG OF HUMAN SPLICING FACTOR SC35; At-SC35; ATSC35; MSJ1.4; MSJ1_4; ortholog of human splicing factor SC35
    Summary
    encodes an SC35-like splicing factor of 35 kD localized to the nuclear specks.
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    Genomic context

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    See SC35 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    9
    Sequence:
    Chromosome: 5; NC_003076.8 (25681202..25683641, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene plant/protein Neighboring gene dentin sialophosphoprotein-like protein Neighboring gene tropomyosin Neighboring gene neuronal PAS domain protein Neighboring gene alternative oxidase 2 Neighboring gene Calmodulin-binding transcription activator protein with CG-1 and Ankyrin domain

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Depletion of Arabidopsis SC35 and SC35-like serine/arginine-rich proteins affects the transcription and splicing of a subset of genes. Yan Q, et al. PLoS Genet, 2017 Mar. PMID 28273088, Free PMC Article
    2. Co-localisation studies of Arabidopsis SR splicing factors reveal different types of speckles in plant cell nuclei. Lorković ZJ, et al. Exp Cell Res, 2008 Oct 15. PMID 18674533
    3. Network of interactions of a novel plant-specific Arg/Ser-rich protein, atRSZ33, with atSC35-like splicing factors. Lopato S, et al. J Biol Chem, 2002 Oct 18. PMID 12176998
    4. AtCyp59 is a multidomain cyclophilin from Arabidopsis thaliana that interacts with SR proteins and the C-terminal domain of the RNA polymerase II. Gullerova M, et al. RNA, 2006 Apr. PMID 16497658, Free PMC Article
    5. Evolutionary conservation of minor U12-type spliceosome between plants and humans. Lorkovic ZJ, et al. RNA, 2005 Jul. PMID 15987817, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_125816.4
    NM_180930.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables mRNA binding HDA PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA splicing NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within mRNA splicing, via spliceosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nuclear speck IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/arginine-rich splicing factor-like protein, putative
    NP_201225.1
    • ortholog of human splicing factor SC35 (SC35); FUNCTIONS IN: RNA binding, nucleotide binding, nucleic acid binding; INVOLVED IN: nuclear mRNA splicing, via spliceosome, RNA splicing; LOCATED IN: cytosol, nuclear speck, membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: SC35-like splicing factor 30A (TAIR:AT3G13570.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
    NP_851261.1
    • ortholog of human splicing factor SC35 (SC35); FUNCTIONS IN: RNA binding, nucleotide binding, nucleic acid binding; INVOLVED IN: nuclear mRNA splicing, via spliceosome, RNA splicing; LOCATED IN: cytosol, nuclear speck, membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: SC35-like splicing factor 30A (TAIR:AT3G13570.1); Has 1404 Blast hits to 650 proteins in 168 species: Archae - 0; Bacteria - 0; Metazoa - 539; Fungi - 520; Plants - 290; Viruses - 0; Other Eukaryotes - 55 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      25681202..25683641 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180930.3 → NP_851261.1  serine/arginine-rich splicing factor-like protein, putative [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851261.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FMG4
      UniProtKB/TrEMBL
      A0A178U800, A0A5S9YI26, Q9FYB1
      Conserved Domains (2) summary
      PHA03307
      Location:204 → 303
      PHA03307; transcriptional regulator ICP4; Provisional
      cd12311
      Location:18 → 90
      RRM_SRSF2_SRSF8; RNA recognition motif (RRM) found in serine/arginine-rich splicing factor SRSF2, SRSF8 and similar proteins

    2. NM_125816.4 → NP_201225.1  serine/arginine-rich splicing factor-like protein, putative [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_201225.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FMG4
      UniProtKB/TrEMBL
      A0A178U800, A0A5S9YI26, Q9FYB1
      Conserved Domains (2) summary
      PHA03307
      Location:204 → 303
      PHA03307; transcriptional regulator ICP4; Provisional
      cd12311
      Location:18 → 90
      RRM_SRSF2_SRSF8; RNA recognition motif (RRM) found in serine/arginine-rich splicing factor SRSF2, SRSF8 and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FMG4.1

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