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    DXPS1 1-deoxy-D-xylulose 5-phosphate synthase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821704, updated on 18-Sep-2024

    Summary

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    Official Symbol
    DXPS1
    Official Full Name
    1-deoxy-D-xylulose 5-phosphate synthase 1
    Primary source
    TAIR:AT3G21500
    Locus tag
    AT3G21500
    See related
    Araport:AT3G21500
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    1-deoxy-D-xylulose 5-phosphate (DXP) synthase 2; 1-deoxy-D-xylulose 5-phosphate synthase 1; DXL1; DXS-like 1; DXS2
    Summary
    Encodes a protein postulated to have 1-deoxy-D-xylulose 5-phosphate synthase activity.
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    Genomic context

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    See DXPS1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Sequence:
    Chromosome: 3; NC_003074.8 (7573560..7576721, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene BRCT domain-containing DNA repair protein Neighboring gene miscRNA Neighboring gene Heavy metal transport/detoxification superfamily protein Neighboring gene histidine-containing phosphotransmitter 1 Neighboring gene ncRNA Neighboring gene transmembrane protein, putative (DUF679 domain membrane protein 1)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional and evolutionary analysis of DXL1, a non-essential gene encoding a 1-deoxy-D-xylulose 5-phosphate synthase like protein in Arabidopsis thaliana. Carretero-Paulet L, et al. Gene, 2013 Jul 15. PMID 23154062
    2. Genome organization in Arabidopsis thaliana: a survey for genes involved in isoprenoid and chlorophyll metabolism. Lange BM, et al. Plant Mol Biol, 2003 Apr. PMID 12777052
    3. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
    4. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. DXPS1 expression levels were high during reproductive development.
      Title: Functional and evolutionary analysis of DXL1, a non-essential gene encoding a 1-deoxy-D-xylulose 5-phosphate synthase like protein in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001338537.1
    NM_113045.3
    NM_180289.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    NOT enables 1-deoxy-D-xylulose-5-phosphate synthase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables 1-deoxy-D-xylulose-5-phosphate synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables 1-deoxy-D-xylulose-5-phosphate synthase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in 1-deoxy-D-xylulose 5-phosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in terpenoid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    1-deoxy-D-xylulose 5-phosphate synthase 1
    NP_566686.2
    • 1-deoxy-D-xylulose 5-phosphate synthase 1 (DXPS1); FUNCTIONS IN: 1-deoxy-D-xylulose-5-phosphate synthase activity; INVOLVED IN: metabolic process, terpenoid biosynthetic process; EXPRESSED IN: stem, embryo, sepal, stamen; EXPRESSED DURING: 4 anthesis, C globular stage; CONTAINS InterPro DOMAIN/s: Transketolase, N-terminal (InterPro:IPR005474), Transketolase, C-terminal (InterPro:IPR005476), Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II (InterPro:IPR009014), Transketolase-like, pyrimidine-binding domain (InterPro:IPR005475), Transketolase binding site (InterPro:IPR020826), Deoxyxylulose-5-phosphate synthase (InterPro:IPR005477), Transketolase-like, C-terminal (InterPro:IPR015941), Dehydrogenase, E1 component (InterPro:IPR001017); BEST Arabidopsis thaliana protein match is: Deoxyxylulose-5-phosphate synthase (TAIR:AT4G15560.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_850620.2
    • 1-deoxy-D-xylulose 5-phosphate synthase 1 (DXPS1); FUNCTIONS IN: 1-deoxy-D-xylulose-5-phosphate synthase activity; INVOLVED IN: metabolic process, terpenoid biosynthetic process; EXPRESSED IN: stem, embryo, sepal, stamen; EXPRESSED DURING: 4 anthesis, C globular stage; CONTAINS InterPro DOMAIN/s: Transketolase, N-terminal (InterPro:IPR005474), Transketolase, C-terminal (InterPro:IPR005476), Transketolase-like, C-terminal (InterPro:IPR015941), Deoxyxylulose-5-phosphate synthase (InterPro:IPR005477), Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II (InterPro:IPR009014), Dehydrogenase, E1 component (InterPro:IPR001017), Transketolase-like, pyrimidine-binding domain (InterPro:IPR005475), Transketolase binding site (InterPro:IPR020826); BEST Arabidopsis thaliana protein match is: Deoxyxylulose-5-phosphate synthase (TAIR:AT4G15560.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      7573560..7576721 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180289.4 → NP_850620.2  1-deoxy-D-xylulose 5-phosphate synthase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850620.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      B5X556, F4IXL8
      Conserved Domains (4) summary
      cd07033
      Location:363 → 516
      TPP_PYR_DXS_TK_like; Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins
      PLN02234
      Location:1 → 641
      PLN02234; 1-deoxy-D-xylulose-5-phosphate synthase
      pfam02780
      Location:536 → 632
      Transketolase_C; Transketolase, C-terminal domain
      pfam13292
      Location:67 → 320
      DXP_synthase_N; 1-deoxy-D-xylulose-5-phosphate synthase

    2. NM_001338537.1 → NP_001327775.1  1-deoxy-D-xylulose 5-phosphate synthase 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VEA6, A0A1I9LTC7, A0A5S9XEA5

    3. NM_113045.3 → NP_566686.2  1-deoxy-D-xylulose 5-phosphate synthase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566686.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      B5X556, F4IXL7
      Conserved Domains (4) summary
      cd07033
      Location:362 → 515
      TPP_PYR_DXS_TK_like; Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins
      PLN02234
      Location:1 → 640
      PLN02234; 1-deoxy-D-xylulose-5-phosphate synthase
      pfam02780
      Location:535 → 631
      Transketolase_C; Transketolase, C-terminal domain
      pfam13292
      Location:67 → 320
      DXP_synthase_N; 1-deoxy-D-xylulose-5-phosphate synthase
    Nucleotide Protein
    Heading Accession and Version

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