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    PUM23 pumilio 23 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843564, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PUM23
    Official Full Name
    pumilio 23
    Primary source
    TAIR:AT1G72320
    Locus tag
    AT1G72320
    See related
    Araport:AT1G72320
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    APUM23; pumilio 23; T9N14.7
    Summary
    Encodes a member of the Arabidopsis Pumilio (APUM) proteins containing PUF domain (eight repeats of approximately 36 amino acids each). PUF proteins regulate both mRNA stability and translation through sequence-specific binding to the 3' UTR of target mRNA transcripts.
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    Genomic context

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    See PUM23 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    12
    Sequence:
    Chromosome: 1; NC_003070.9 (27228059..27233167, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Leucine-rich receptor-like protein kinase family protein Neighboring gene RING/U-box superfamily protein Neighboring gene alanine aminotransferase 2 Neighboring gene NagB/RpiA/CoA transferase-like superfamily protein Neighboring gene MADS-box transcription factor family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structural basis for the specific recognition of 18S rRNA by APUM23. Bao H, et al. Nucleic Acids Res, 2017 Nov 16. PMID 29036323, Free PMC Article
    2. APUM23, a PUF family protein, functions in leaf development and organ polarity in Arabidopsis. Huang T, et al. J Exp Bot, 2014 Mar. PMID 24449383, Free PMC Article
    3. APUM23, a nucleolar Puf domain protein, is involved in pre-ribosomal RNA processing and normal growth patterning in Arabidopsis. Abbasi N, et al. Plant J, 2010 Dec. PMID 21143677
    4. Structural and functional similarities and differences in nucleolar Pumilio RNA-binding proteins between Arabidopsis and the charophyte Chara corallina. Park SH, et al. BMC Plant Biol, 2020 May 24. PMID 32448230, Free PMC Article
    5. Molecular Basis for a Cell Fate Switch in Response to Impaired Ribosome Biogenesis in the Arabidopsis Root Epidermis. Wang W, et al. Plant Cell, 2020 Jul. PMID 32371546, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Molecular Basis for a Cell Fate Switch in Response to Impaired Ribosome Biogenesis in the Arabidopsis Root Epidermis.
      Title: Molecular Basis for a Cell Fate Switch in Response to Impaired Ribosome Biogenesis in the Arabidopsis Root Epidermis.
    2. Structural and functional similarities and differences in nucleolar Pumilio RNA-binding proteins between Arabidopsis and the charophyte Chara corallina.
      Title: Structural and functional similarities and differences in nucleolar Pumilio RNA-binding proteins between Arabidopsis and the charophyte Chara corallina.
    3. Data show that the complete RNA target sequence of APUM23 comprises 11 nt in 18S rRNA at positions 1141-1151.
      Title: Structural basis for the specific recognition of 18S rRNA by APUM23.
    4. APUM23 is important for organ growth and pattern formation in Arabidopsis.
      Title: APUM23, a PUF family protein, functions in leaf development and organ polarity in Arabidopsis.
    5. APUM23 localizes exclusively to the nucleolus and is involved in rRNA processing. Disruption affects plant growth and development.
      Title: APUM23, a nucleolar Puf domain protein, is involved in pre-ribosomal RNA processing and normal growth patterning in Arabidopsis.
    Submit: New GeneRIF Correction

    General gene information

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    NM_001334523.1
    NM_105891.3
    NM_179547.5
    NM_202401.1

    Gene Ontology Provided by TAIR

    Process Evidence Code Pubs
    acts_upstream_of_or_within response to glucose IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to sucrose IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    pumilio 23
    NP_177376.1
    • pumilio 23 (PUM23); FUNCTIONS IN: RNA binding, binding; INVOLVED IN: biological_process unknown; LOCATED IN: nucleolus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Pumilio RNA-binding repeat (InterPro:IPR001313), Armadillo-like helical (InterPro:IPR011989), Armadillo-type fold (InterPro:IPR016024); Has 376 Blast hits to 376 proteins in 171 species: Archae - 0; Bacteria - 0; Metazoa - 121; Fungi - 142; Plants - 69; Viruses - 0; Other Eukaryotes - 44 (source: NCBI BLink).
    NP_849878.2
    • pumilio 23 (PUM23); FUNCTIONS IN: RNA binding, binding; INVOLVED IN: biological_process unknown; LOCATED IN: nucleolus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Pumilio RNA-binding repeat (InterPro:IPR001313), Armadillo-like helical (InterPro:IPR011989), Armadillo-type fold (InterPro:IPR016024); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_974130.1
    • pumilio 23 (PUM23); FUNCTIONS IN: RNA binding, binding; INVOLVED IN: biological_process unknown; LOCATED IN: nucleolus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Pumilio RNA-binding repeat (InterPro:IPR001313), Armadillo-like helical (InterPro:IPR011989), Armadillo-type fold (InterPro:IPR016024); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      27228059..27233167 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_179547.5 → NP_849878.2  pumilio 23 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849878.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WK29
      Conserved Domains (1) summary
      cl21719
      Location:323 → 581
      Pumilio; Pumilio-family RNA binding domain

    2. NM_001334523.1 → NP_001321803.1  pumilio 23 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q3E7J5, Q3ECD8, Q9C552
      UniProtKB/TrEMBL
      A0A654EN94

    3. NM_105891.3 → NP_177376.1  pumilio 23 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177376.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q3E7J5, Q3ECD8, Q9C552
      UniProtKB/TrEMBL
      A0A654EN94
      Conserved Domains (1) summary
      cl21719
      Location:345 → 603
      Pumilio; Pumilio-family RNA binding domain

    4. NM_202401.1 → NP_974130.1  pumilio 23 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974130.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WK29
      Conserved Domains (1) summary
      cl21719
      Location:323 → 581
      Pumilio; Pumilio-family RNA binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9C552.1

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