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    OBE2 potyvirus VPg interacting protein (DUF1423) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834868, updated on 18-Sep-2024

    Summary

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    Official Symbol
    OBE2
    Official Full Name
    potyvirus VPg interacting protein (DUF1423)
    Primary source
    TAIR:AT5G48160
    Locus tag
    AT5G48160
    See related
    Araport:AT5G48160
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MIF21.5; MIF21_5; OBERON2
    Summary
    Encodes a nuclear PHD finger protein that is functionally redundant with OBE1 and plays an important role in the maintenance and/or establishment of the root and shoot apical meristems.
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    Genomic context

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    See OBE2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    3
    Sequence:
    Chromosome: 5; NC_003076.8 (19527767..19530430, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Pectin lyase-like superfamily protein Neighboring gene GRAS family transcription factor Neighboring gene F-box family protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Arabidopsis OBERON1 and OBERON2 genes encode plant homeodomain finger proteins and are required for apical meristem maintenance. Saiga S, et al. Development, 2008 May. PMID 18403411
    2. A cysteine-rich plant protein potentiates Potyvirus movement through an interaction with the virus genome-linked protein VPg. Dunoyer P, et al. J Virol, 2004 Mar. PMID 14963126, Free PMC Article
    3. Control of embryonic meristem initiation in Arabidopsis by PHD-finger protein complexes. Saiga S, et al. Development, 2012 Apr. PMID 22378640
    4. Arabidopsis plant homeodomain finger proteins operate downstream of auxin accumulation in specifying the vasculature and primary root meristem. Thomas CL, et al. Plant J, 2009 Aug. PMID 19392692
    5. The non-JAZ TIFY protein TIFY8 from Arabidopsis thaliana is a transcriptional repressor. Cuéllar Pérez A, et al. PLoS One, 2014. PMID 24416306, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. OBE1 and OBE2 operate downstream of auxin canalization in the early stages of embryo development. Mutants are defective in vascular patterning.
      Title: Arabidopsis plant homeodomain finger proteins operate downstream of auxin accumulation in specifying the vasculature and primary root meristem.
    2. OBE1 and OBE2 genes are functionally redundant and crucial for the maintenance and/or establishment of both the shoot and root meristems. [OBE2] [OBERON2]
      Title: The Arabidopsis OBERON1 and OBERON2 genes encode plant homeodomain finger proteins and are required for apical meristem maintenance.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001036954.1
    NM_124190.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within embryo development ending in seed dormancy IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within maintenance of root meristem identity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within maintenance of shoot apical meristem identity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within primary root development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of gene expression IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within root meristem specification IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in transport of virus in host, cell to cell IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    potyvirus VPg interacting protein (DUF1423)
    NP_001032031.1
    • OBERON2 (OBE2); FUNCTIONS IN: zinc ion binding; INVOLVED IN: in 6 processes; LOCATED IN: nucleus; EXPRESSED IN: 6 plant structures; EXPRESSED DURING: seedling growth, C globular stage, B proembryo stage, D bilateral stage, E expanded cotyledon stage; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1423, plant (InterPro:IPR004082), Zinc finger, PHD-type (InterPro:IPR001965); BEST Arabidopsis thaliana protein match is: Protein of unknown function (DUF1423) (TAIR:AT3G07780.1); Has 2495 Blast hits to 2042 proteins in 337 species: Archae - 17; Bacteria - 243; Metazoa - 768; Fungi - 203; Plants - 349; Viruses - 34; Other Eukaryotes - 881 (source: NCBI BLink).
    NP_199627.1
    • OBERON2 (OBE2); FUNCTIONS IN: zinc ion binding; INVOLVED IN: in 6 processes; LOCATED IN: nucleus; EXPRESSED IN: 6 plant structures; EXPRESSED DURING: seedling growth, C globular stage, B proembryo stage, D bilateral stage, E expanded cotyledon stage; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1423, plant (InterPro:IPR004082), Zinc finger, PHD-type (InterPro:IPR001965); BEST Arabidopsis thaliana protein match is: Protein of unknown function (DUF1423) (TAIR:AT3G07780.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      19527767..19530430 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124190.4 → NP_199627.1  potyvirus VPg interacting protein (DUF1423) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199627.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B9DH01, Q0WU99, Q570W2, Q9LUB7
      UniProtKB/TrEMBL
      A0A178U8A7, A0A5S9YCC2
      Conserved Domains (2) summary
      pfam07227
      Location:198 → 323
      PHD_Oberon; PHD - plant homeodomain finger protein
      pfam16312
      Location:416 → 551
      Oberon_cc; Coiled-coil region of Oberon

    2. NM_001036954.1 → NP_001032031.1  potyvirus VPg interacting protein (DUF1423) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001032031.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B9DH01, Q0WU99, Q570W2, Q9LUB7
      UniProtKB/TrEMBL
      A0A178U8A7, A0A5S9YCC2
      Conserved Domains (2) summary
      pfam07227
      Location:198 → 323
      PHD_Oberon; PHD - plant homeodomain finger protein
      pfam16312
      Location:416 → 551
      Oberon_cc; Coiled-coil region of Oberon
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LUB7.1

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