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    DL1 dynamin-like protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834213, updated on 18-Sep-2024

    Summary

    Official Symbol
    DL1
    Official Full Name
    dynamin-like protein
    Primary source
    TAIR:AT5G42080
    Locus tag
    AT5G42080
    See related
    Araport:AT5G42080
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ADL1; ADL1A; AG68; DRP1A; dynamin-like protein; DYNAMIN-RELATED PROTEIN 1A; MJC20.19; MJC20_19; RADIAL SWELLING 9; RSW9
    Summary
    Encodes a dynamin-like protein related to phragmoplastin. Mutations in this gene, in combination with mutation in ADL1E, result in defects in embryogenesis, cell plate formation and trichome branching. Also controls vascular patterning in combination with VAN3 and GNOM. DRP2B and DRP1A participate together in clathrin-coated vesicle formation during endocytosis.
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    Genomic context

    See DL1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    16
    Sequence:
    Chromosome: 5; NC_003076.8 (16820284..16825016, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene DEK, chromatin associated protein Neighboring gene uncharacterized protein Neighboring gene Lung seven transmembrane receptor family protein Neighboring gene ncRNA Neighboring gene beta-1,3-glucanase

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    NM_001203519.1
    NM_123573.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GTPase activity PubMed 
    enables GTPase activity  
    enables clathrin binding PubMed 
    enables protein binding PubMed 
    enables protein histidine kinase binding PubMed 
    Process Evidence Code Pubs
    involved_in cell plate formation involved in plant-type cell wall biogenesis PubMed 
    acts_upstream_of_or_within cell plate formation involved in plant-type cell wall biogenesis PubMed 
    involved_in cell plate formation involved in plant-type cell wall biogenesis PubMed 
    involved_in cellular response to boron-containing substance levels PubMed 
    acts_upstream_of_or_within clathrin-dependent endocytosis PubMed 
    involved_in clathrin-dependent endocytosis PubMed 
    acts_upstream_of_or_within cytokinesis by cell plate formation PubMed 
    acts_upstream_of_or_within embryo development ending in seed dormancy PubMed 
    involved_in intracellular protein transport PubMed 
    involved_in regulation of endocytosis PubMed 
    acts_upstream_of_or_within regulation of establishment of cell polarity PubMed 
    involved_in regulation of lipid localization PubMed 
    involved_in regulation of phragmoplast microtubule organization PubMed 
    involved_in regulation of plant-type cell wall organization or biogenesis PubMed 
    involved_in response to boron-containing substance PubMed 
    acts_upstream_of_or_within root hair initiation PubMed 
    involved_in stigma development PubMed 
    acts_upstream_of_or_within trichome branching PubMed 
    acts_upstream_of_or_within xylem and phloem pattern formation PubMed 

    General protein information

    Preferred Names
    dynamin-like protein
    NP_001190448.1
    • dynamin-like protein (DL1); CONTAINS InterPro DOMAIN/s: Dynamin GTPase effector (InterPro:IPR003130), Dynamin, GTPase region, conserved site (InterPro:IPR019762), GTPase effector domain, GED (InterPro:IPR020850), Dynamin, GTPase domain (InterPro:IPR001401), Dynamin central region (InterPro:IPR000375); BEST Arabidopsis thaliana protein match is: DYNAMIN-like 1B (TAIR:AT3G61760.1).
    NP_568602.3
    • dynamin-like protein (DL1); FUNCTIONS IN: protein binding, clathrin binding, GTP binding, GTPase activity; INVOLVED IN: in 6 processes; LOCATED IN: in 6 components; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Dynamin, GTPase domain (InterPro:IPR001401), Dynamin, GTPase region, conserved site (InterPro:IPR019762), Dynamin central region (InterPro:IPR000375); BEST Arabidopsis thaliana protein match is: DYNAMIN-like 1B (TAIR:AT3G61760.1); Has 2738 Blast hits to 2718 proteins in 315 species: Archae - 2; Bacteria - 44; Metazoa - 1052; Fungi - 806; Plants - 508; Viruses - 0; Other Eukaryotes - 326 (source: NCBI BLink).
    NP_851120.1
    • dynamin-like protein (DL1); FUNCTIONS IN: protein binding, clathrin binding, GTP binding, GTPase activity; INVOLVED IN: in 6 processes; LOCATED IN: in 6 components; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Dynamin GTPase effector (InterPro:IPR003130), Dynamin, GTPase domain (InterPro:IPR001401), Dynamin, GTPase region, conserved site (InterPro:IPR019762), GTPase effector domain, GED (InterPro:IPR020850), Dynamin central region (InterPro:IPR000375); BEST Arabidopsis thaliana protein match is: DYNAMIN-like 1B (TAIR:AT3G61760.1); Has 2870 Blast hits to 2761 proteins in 321 species: Archae - 2; Bacteria - 66; Metazoa - 1056; Fungi - 810; Plants - 578; Viruses - 0; Other Eukaryotes - 358 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      16820284..16825016 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180789.3 → NP_851120.1  dynamin-like protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851120.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P42697, Q0WLG2, Q1EBU0, Q39118, Q8L9V5, Q8LPS7
      UniProtKB/TrEMBL
      A0A178UEJ4, A0A5S9YAD2
      Conserved Domains (3) summary
      smart00302
      Location:513 → 606
      GED; Dynamin GTPase effector domain
      cd08771
      Location:33 → 300
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
      pfam01031
      Location:222 → 495
      Dynamin_M; Dynamin central region
    2. NM_001344434.1 → NP_001331306.1  dynamin-like protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P42697, Q0WLG2, Q1EBU0, Q39118, Q8L9V5, Q8LPS7
      UniProtKB/TrEMBL
      A0A178UEJ4, A0A5S9YAD2
      Conserved Domains (3) summary
      smart00302
      Location:513 → 606
      GED; Dynamin GTPase effector domain
      cd08771
      Location:33 → 300
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
      pfam01031
      Location:222 → 495
      Dynamin_M; Dynamin central region
    3. NM_001203519.1 → NP_001190448.1  dynamin-like protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190448.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4K015
      Conserved Domains (4) summary
      smart00302
      Location:507 → 600
      GED; Dynamin GTPase effector domain
      cd08771
      Location:33 → 300
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
      COG0699
      Location:84 → 318
      CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
      pfam01031
      Location:223 → 491
      Dynamin_M; Dynamin central region
    4. NM_123573.3 → NP_568602.3  dynamin-like protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568602.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P42697
      Conserved Domains (3) summary
      cd08771
      Location:33 → 300
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
      COG0699
      Location:84 → 318
      CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
      pfam01031
      Location:223 → 429
      Dynamin_M; Dynamin central region
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