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    MED10A Mediator complex, subunit Med10 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834196, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MED10A
    Official Full Name
    Mediator complex, subunit Med10
    Primary source
    TAIR:AT5G41910
    Locus tag
    AT5G41910
    See related
    Araport:AT5G41910
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MJC20.1; MJC20_1
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    Genomic context

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    See MED10A in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    7
    Sequence:
    Chromosome: 5; NC_003076.8 (16777691..16779295, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene GRAS family transcription factor Neighboring gene Ypt/Rab-GAP domain of gyp1p superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Biochemical and redox characterization of the mediator complex and its associated transcription factor GeBPL, a GLABROUS1 enhancer binding protein. Shaikhali J, et al. Biochem J, 2015 Jun 15. PMID 25877331
    2. Purification of a plant mediator from Arabidopsis thaliana identifies PFT1 as the Med25 subunit. Bäckström S, et al. Mol Cell, 2007 Jun 8. PMID 17560376
    3. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    • At5g41920_Arabidopsis_lyrata_ssp._lyrata_CAN10 (e-PCR)
    • At5g41920_Arabidopsis_lyrata_ssp._petraea_GER1 (e-PCR)
    NM_001344425.1
    NM_001344426.1
    NM_123556.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables transcription coregulator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of mediator complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Mediator complex, subunit Med10
    NP_199006.1
    • MED10A; FUNCTIONS IN: RNA polymerase II transcription mediator activity; INVOLVED IN: regulation of transcription from RNA polymerase II promoter; LOCATED IN: mediator complex; CONTAINS InterPro DOMAIN/s: Mediator complex, subunit Med10 (InterPro:IPR019145); BEST Arabidopsis thaliana protein match is: Mediator complex, subunit Med10 (TAIR:AT1G26665.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      16777691..16779295 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_123556.3 → NP_199006.1  Mediator complex, subunit Med10 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199006.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FHZ2
      UniProtKB/TrEMBL
      A0A178U9X0, A0A5S9YAG0
      Conserved Domains (1) summary
      pfam09748
      Location:43 → 156
      Med10; Transcription factor subunit Med10 of Mediator complex

    2. NM_001344425.1 → NP_001331138.1  Mediator complex, subunit Med10 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FHZ2
      UniProtKB/TrEMBL
      A0A178U9X0, A0A5S9YAG0
      Conserved Domains (1) summary
      pfam09748
      Location:43 → 156
      Med10; Transcription factor subunit Med10 of Mediator complex

    3. NM_001344426.1 → NP_001331137.1  Mediator complex, subunit Med10 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FHZ2
      UniProtKB/TrEMBL
      A0A178U9X0, A0A5S9YAG0
      Conserved Domains (1) summary
      pfam09748
      Location:43 → 156
      Med10; Transcription factor subunit Med10 of Mediator complex
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FHZ2.1

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