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    PYL1 PYR1-like 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834722, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PYL1
    Official Full Name
    PYR1-like 1
    Primary source
    TAIR:AT5G46790
    Locus tag
    AT5G46790
    See related
    Araport:AT5G46790
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MZA15.21; MZA15_21; PYR1-like 1; RCAR12; regulatory components of ABA receptor 12
    Summary
    Encodes a member of the PYR (pyrabactin resistance)/PYL(PYR1-like)/RCAR (regulatory components of ABA receptor) family proteins with 14 members. PYR/PYL/RCAR family proteins function as abscisic acid sensors. Mediate ABA-dependent regulation of protein phosphatase 2Cs ABI1 and ABI2.
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    Genomic context

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    See PYL1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    1
    Sequence:
    Chromosome: 5; NC_003076.8 (18983540..18984923, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene VQ motif-containing protein Neighboring gene ncRNA Neighboring gene microspore-specific promoter 2 Neighboring gene Mitochondrial substrate carrier family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Modeling-based identification of a Raptor-binding motif present in Arabidopsis ABA receptor PYL1. Kim J, et al. Biochem Biophys Res Commun, 2020 Dec 17. PMID 33070969
    2. Structural basis of abscisic acid signalling. Miyazono K, et al. Nature, 2009 Dec 3. PMID 19855379
    3. Responses of PYR/PYL/RCAR ABA Receptors to Contrasting stresses, Heat and Cold in Arabidopsis. Zhang Q, et al. Plant Signal Behav, 2019. PMID 31552801, Free PMC Article
    4. Structural insights into the mechanism of abscisic acid signaling by PYL proteins. Yin P, et al. Nat Struct Mol Biol, 2009 Dec. PMID 19893533
    5. Engineering the ABA plant stress pathway for regulation of induced proximity. Liang FS, et al. Sci Signal, 2011 Mar 15. PMID 21406691, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Modeling-based identification of a Raptor-binding motif present in Arabidopsis ABA receptor PYL1.
      Title: Modeling-based identification of a Raptor-binding motif present in Arabidopsis ABA receptor PYL1.
    2. RCAR12 and RCAR13, the abscissic acid receptors, may play the positive roles in regulating the extreme temperature, including cold and high temperature in Arabidopsis.
      Title: Responses of PYR/PYL/RCAR ABA Receptors to Contrasting stresses, Heat and Cold in Arabidopsis.
    3. In the ternary complex of abscisic acid-PYL1-ABI1, the CL2 loop of PYL1 is located near the active site of ABI1, blocking the entry of substrate proteins. [PYL1]
      Title: Structural insights into the mechanism of abscisic acid signaling by PYL proteins.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001344698.1
    NM_124049.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables abscisic acid binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables abscisic acid binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein homodimerization activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables protein phosphatase inhibitor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein phosphatase regulator activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables signaling receptor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables signaling receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in abscisic acid-activated signaling pathway IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within abscisic acid-activated signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within defense response IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    PYR1-like 1
    NP_199491.2
    • PYR1-like 1 (PYL1); CONTAINS InterPro DOMAIN/s: Polyketide cyclase/dehydrase (InterPro:IPR019587); BEST Arabidopsis thaliana protein match is: Polyketide cyclase/dehydrase and lipid transport superfamily protein (TAIR:AT4G17870.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      18983540..18984923 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124049.5 → NP_199491.2  PYR1-like 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199491.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8VZS8, Q9FIP6
      UniProtKB/TrEMBL
      A0A178ULZ2, A0A654G8V4, A0A7G2FKN3
      Conserved Domains (1) summary
      cd07821
      Location:57 → 206
      PYR_PYL_RCAR_like; Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins

    2. NM_001344698.1 → NP_001331305.1  PYR1-like 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8VZS8, Q9FIP6
      UniProtKB/TrEMBL
      A0A178ULZ2, A0A654G8V4, A0A7G2FKN3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8VZS8.1

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