VDAC4 voltage dependent anion channel 4 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: VDAC4
Official Full Name: voltage dependent anion channel 4
Primary source: TAIR:AT5G57490
Locus tag: AT5G57490
See related: Araport:AT5G57490
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ARABIDOPSIS THALIANA VOLTAGE DEPENDENT ANION CHANNEL 4; ATVDAC4; MUA2.6; MUA2_6; voltage dependent anion channel 4
Summary: Encodes a voltage-dependent anion channel (VDAC: AT3G01280/VDAC1, AT5G67500/VDAC2, AT5G15090/VDAC3, AT5G57490/VDAC4, AT5G15090/VDAC5). VDACs are reported to be porin-type, beta-barrel diffusion pores. They are prominently localized in the outer mitochondrial membrane and are involved in metabolite exchange between the organelle and the cytosol.
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Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

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AtVDAC4 has a main function in mitochondria
Title: Voltage-dependent-anion-channels (VDACs) in Arabidopsis have a dual localization in the cell but show a distinct role in mitochondria.
VDAC2 and VDAC4 are important for leaf development, the mitochondrial membrane potential, and pollen development.
Title: Molecular and genetic characterization of the gene family encoding the voltage-dependent anion channel in Arabidopsis.

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NM_125130.3

Function	Evidence Code	Pubs
enables voltage-gated monoatomic anion channel activity	IMP Inferred from Mutant Phenotype more info	PubMed

Process	Evidence Code	Pubs
involved_in monoatomic anion transmembrane transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within response to bacterium	IEP Inferred from Expression Pattern more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrion	HDA more info	PubMed
located_in mitochondrion	IDA Inferred from Direct Assay more info	PubMed
located_in mitochondrion	ISM Inferred from Sequence Model more info
located_in plasma membrane	HDA more info	PubMed
located_in plastid	HDA more info	PubMed

NP_200557.1

voltage dependent anion channel 4 (VDAC4); FUNCTIONS IN: voltage-gated anion channel activity; INVOLVED IN: response to bacterium, anion transport; LOCATED IN: mitochondrial outer membrane, mitochondrion, plasma membrane, membrane; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Porin, eukaryotic type (InterPro:IPR001925); BEST Arabidopsis thaliana protein match is: voltage dependent anion channel 2 (TAIR:AT5G67500.1); Has 864 Blast hits to 864 proteins in 195 species: Archae - 0; Bacteria - 0; Metazoa - 407; Fungi - 143; Plants - 294; Viruses - 0; Other Eukaryotes - 20 (source: NCBI BLink).

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The following sections contain reference sequences that belong to a specific genome build. Explain