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    CYCD3;2 CYCLIN D3;2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836861, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CYCD3;2
    Official Full Name
    CYCLIN D3;2
    Primary source
    TAIR:AT5G67260
    Locus tag
    AT5G67260
    See related
    Araport:AT5G67260
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    CYCLIN D3;2; K3G17.2; K3G17_2
    Summary
    Encode CYCD3;2, a CYCD3 D-type cyclin. Important for determining cell number in developing lateral organs. Mediating cytokinin effects in apical growth and development.
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    Genomic context

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    See CYCD3;2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (26836139..26839597)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene SKP1/ASK1-interacting protein 2 Neighboring gene uncharacterized protein Neighboring gene end binding protein 1C Neighboring gene receptor-like kinase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis Leaf Flatness Is Regulated by PPD2 and NINJA through Repression of CYCLIN D3 Genes. Baekelandt A, et al. Plant Physiol, 2018 Sep. PMID 29991485, Free PMC Article
    2. Arabidopsis CYCD3 D-type cyclins link cell proliferation and endocycles and are rate-limiting for cytokinin responses. Dewitte W, et al. Proc Natl Acad Sci U S A, 2007 Sep 4. PMID 17726100, Free PMC Article
    3. D-type cyclins control cell division and developmental rate during Arabidopsis seed development. Collins C, et al. J Exp Bot, 2012 Jun. PMID 22412186, Free PMC Article
    4. Requirement for A-type cyclin-dependent kinase and cyclins for the terminal division in the stomatal lineage of Arabidopsis. Yang K, et al. J Exp Bot, 2014 Jun. PMID 24687979, Free PMC Article
    5. Functional modules in the Arabidopsis core cell cycle binary protein-protein interaction network. Boruc J, et al. Plant Cell, 2010 Apr. PMID 20407024, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Transcriptional regulator PEAPOD2 (PPD2) and NOVEL INTERACTOR OF JAZ (NINJA) mutants have a similar increase in the expression of CYCLIN D3;2 (CYCD3;2).
      Title: Arabidopsis Leaf Flatness Is Regulated by PPD2 and NINJA through Repression of CYCLIN D3 Genes.
    2. CDKA;1 and CYCD3;2 are required for the terminal division in the stomatal lineage.
      Title: Requirement for A-type cyclin-dependent kinase and cyclins for the terminal division in the stomatal lineage of Arabidopsis.
    3. CYCD3 activity is important for determining cell number in developing lateral organs and the relative contribution of the alternative processes of cell production and cell expansion to overall organ growth
      Title: Arabidopsis CYCD3 D-type cyclins link cell proliferation and endocycles and are rate-limiting for cytokinin responses.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001345820.1
    NM_126126.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in guard mother cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of cell population proliferation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of leaf morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within seed development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    CYCLIN D3;2
    NP_201527.1
    • CYCLIN D3;2 (CYCD3;2); FUNCTIONS IN: cyclin-dependent protein kinase activity; INVOLVED IN: regulation of cell cycle, regulation of cell proliferation; LOCATED IN: nucleus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cyclin, C-terminal (InterPro:IPR004367), Cyclin D (InterPro:IPR015451), Cyclin-like (InterPro:IPR011028), Cyclin-related (InterPro:IPR013763), Cyclin, N-terminal (InterPro:IPR006671), Cyclin (InterPro:IPR006670); BEST Arabidopsis thaliana protein match is: CYCLIN D3;3 (TAIR:AT3G50070.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      26836139..26839597
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_126126.3 → NP_201527.1  CYCLIN D3;2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_201527.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FGQ7
      UniProtKB/TrEMBL
      A0A178U8G6, A0A5S9YHR9, A0A654GEV1
      Conserved Domains (2) summary
      cd20543
      Location:95 → 193
      CYCLIN_AtCycD-like_rpt1; first cyclin box found in plant cyclin-delta family
      cd20544
      Location:198 → 288
      CYCLIN_AtCycD-like_rpt2; second cyclin box found in plant cyclin-delta family

    2. NM_001345820.1 → NP_001331659.1  CYCLIN D3;2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178U8G6, A0A1P8BEM5
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FGQ7.1

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