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    RABC2A RAB GTPase homolog C2A [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831810, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RABC2A
    Official Full Name
    RAB GTPase homolog C2A
    Primary source
    TAIR:AT5G03530
    Locus tag
    AT5G03530
    See related
    Araport:AT5G03530
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA RAB GTPASE HOMOLOG C2A; ATRAB; ATRAB ALPHA; ATRAB18B; ATRABC2A; F12E4.310; F12E4_310; RAB GTPase homolog C2A
    Summary
    Encodes a member of the Rab GTPase family of proteins. This protein interacts with the tail region of a myosin XI protein (AT5G43900) in a GTP-dependent manner. CFP:RabC2a appears to co-localize with peroxisomes.
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    Genomic context

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    See RABC2A in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (885437..887700, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Mediator complex, subunit Med7 Neighboring gene C2H2-type zinc finger family protein Neighboring gene RAB GTPase homolog 8C Neighboring gene exocyst subunit exo70 family protein A1 Neighboring gene expressed in response to phosphate starvation protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An isoform of Arabidopsis myosin XI interacts with small GTPases in its C-terminal tail region. Hashimoto K, et al. J Exp Bot, 2008. PMID 18703495, Free PMC Article
    2. CHARACTERIZATION OF A RABE (RAS GENE FROM RAT BRAIN E) GTPASE EXPRESSED DURING MORPHOGENESIS IN THE UNICELLULAR GREEN ALGA MICRASTERIAS DENTICULATA (ZYGNEMATOPHYCEAE, STREPTOPHYTA)(1). Vannerum K, et al. J Phycol, 2012 Jun. PMID 27011085
    3. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AtRabD1 and AtRabC2a interact with the C-terminal tail region of MYA2.
      Title: An isoform of Arabidopsis myosin XI interacts with small GTPases in its C-terminal tail region.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001342711.1
    NM_120433.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GTP-dependent protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables myosin XI tail binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in peroxisome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane HDA PubMed 

    General protein information

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    Preferred Names
    RAB GTPase homolog C2A
    NP_568121.1
    • RAB GTPase homolog C2A (RABC2A); FUNCTIONS IN: GTP binding, myosin XI tail binding, GTP-dependent protein binding; INVOLVED IN: protein transport, small GTPase mediated signal transduction, regulation of transcription, DNA-dependent; LOCATED IN: peroxisome; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Ras (InterPro:IPR013753), Small GTP-binding protein (InterPro:IPR005225), Ras GTPase (InterPro:IPR001806), Ras small GTPase, Rab type (InterPro:IPR003579), Small GTPase (InterPro:IPR020851), RNA polymerase sigma factor 54, interaction (InterPro:IPR002078), Rab18 (InterPro:IPR015598); BEST Arabidopsis thaliana protein match is: RAB GTPase homolog C2B (TAIR:AT3G09910.3); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      885437..887700 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120433.3 → NP_568121.1  RAB GTPase homolog C2A [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568121.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49841
      UniProtKB/TrEMBL
      A0A178UJG3, A0A5S9Y1K2
      Conserved Domains (1) summary
      PLN03118
      Location:1 → 210
      PLN03118; Rab family protein; Provisional

    2. NM_001342711.1 → NP_001332165.1  RAB GTPase homolog C2A [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49841
      UniProtKB/TrEMBL
      A0A178UJG3, A0A5S9Y1K2
      Conserved Domains (1) summary
      PLN03118
      Location:1 → 210
      PLN03118; Rab family protein; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O49841.1

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