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    DHNAT2 Thioesterase superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834953, updated on 18-Sep-2024

    Summary

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    Official Symbol
    DHNAT2
    Official Full Name
    Thioesterase superfamily protein
    Primary source
    TAIR:AT5G48950
    Locus tag
    AT5G48950
    See related
    Araport:AT5G48950
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    DHNA-CoA thioesterase 2; K19E20.6; K19E20_6
    Summary
    Encodes one of the two functional DHNA-CoA (1,4-dihydroxy-2-naphthoyl-CoA) thioesterases found in Arabidopsis.
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    Genomic context

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    See DHNAT2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    2
    Sequence:
    Chromosome: 5; NC_003076.8 (19845999..19847435)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Leucine-rich repeat transmembrane protein kinase family protein Neighboring gene low-molecular-weight cysteine-rich 46 Neighboring gene low-molecular-weight cysteine-rich 86 Neighboring gene HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Phylloquinone (vitamin K(1) ) biosynthesis in plants: two peroxisomal thioesterases of Lactobacillales origin hydrolyze 1,4-dihydroxy-2-naphthoyl-CoA. Widhalm JR, et al. Plant J, 2012 Jul. PMID 22372525
    2. Alternative splicing affects the targeting sequence of peroxisome proteins in Arabidopsis. An C, et al. Plant Cell Rep, 2017 Jul. PMID 28352967
    3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AtDHNAT1 (AT1G48320) and AtDHNAT2 (AT5G48950) participate in phylloquinone biosynthesis in Arabidopsis.
      Title: Phylloquinone (vitamin K(1) ) biosynthesis in plants: two peroxisomal thioesterases of Lactobacillales origin hydrolyze 1,4-dihydroxy-2-naphthoyl-CoA.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    NM_124272.3
    NM_203182.2

    Gene Ontology Provided by TAIR

    Process Evidence Code Pubs
    involved_in phylloquinone biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within phylloquinone biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein homotetramerization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    NOT located_in peroxisome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in peroxisome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Thioesterase superfamily protein
    NP_199706.1
    • Thioesterase superfamily protein; CONTAINS InterPro DOMAIN/s: Thioesterase superfamily (InterPro:IPR006683), Phenylacetic acid degradation-related protein (InterPro:IPR003736); BEST Arabidopsis thaliana protein match is: Thioesterase superfamily protein (TAIR:AT1G48320.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
    NP_974911.1
    • Thioesterase superfamily protein; CONTAINS InterPro DOMAIN/s: Thioesterase superfamily (InterPro:IPR006683), Phenylacetic acid degradation-related protein (InterPro:IPR003736); BEST Arabidopsis thaliana protein match is: Thioesterase superfamily protein (TAIR:AT1G48320.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      19845999..19847435
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_203182.2 → NP_974911.1  Thioesterase superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974911.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178U9Y4, Q3E8E1
      Conserved Domains (1) summary
      cl00509
      Location:10 → 110
      hot_dog; The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated ...

    2. NM_124272.3 → NP_199706.1  Thioesterase superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199706.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FI76
      UniProtKB/TrEMBL
      A0A178U9C4, A0A5S9YCU4, A0A654G9C0
      Conserved Domains (2) summary
      pfam13622
      Location:42 → 112
      4HBT_3; Thioesterase-like superfamily
      cl00509
      Location:10 → 153
      hot_dog; The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FI76.1

    Gene LinkOut

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