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    Major Facilitator Superfamily with SPX (SYG1/Pho81/XPR1) domain-containing protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828398, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Major Facilitator Superfamily with SPX (SYG1/Pho81/XPR1) domain-containing protein
    Primary source
    TAIR:AT4G22990
    Locus tag
    AT4G22990
    See related
    Araport:AT4G22990
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F7H19.170; F7H19_170
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    11
    Sequence:
    Chromosome: 4; NC_003075.7 (12048160..12051891, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene separase Neighboring gene molybdenum cofactor sulfurase-like protein Neighboring gene Calcineurin-like metallo-phosphoesterase superfamily protein Neighboring gene uncharacterized protein Neighboring gene UDP-galactose transporter 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Vacuolar Phosphate Transporters Contribute to Systemic Phosphate Homeostasis Vital for Reproductive Development in Arabidopsis. Luan M, et al. Plant Physiol, 2019 Feb. PMID 30552198, Free PMC Article
    2. Identification of plant vacuolar transporters mediating phosphate storage. Liu TY, et al. Nat Commun, 2016 Mar 31. PMID 27029856, Free PMC Article
    3. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. VPT3 (AT4G22990) contributes to cytosol-to-vacuole phosphate partitioning and reproductive development.
      Title: Vacuolar Phosphate Transporters Contribute to Systemic Phosphate Homeostasis Vital for Reproductive Development in Arabidopsis.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_118428.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within transmembrane phosphate ion transport from cytosol to vacuole IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within transmembrane phosphate ion transport from cytosol to vacuole IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plant-type vacuole membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Major Facilitator Superfamily with SPX (SYG1/Pho81/XPR1) domain-containing protein
    NP_001190805.1
    • Major Facilitator Superfamily with SPX (SYG1/Pho81/XPR1) domain-containing protein; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: transmembrane transport; LOCATED IN: cellular_component unknown; CONTAINS InterPro DOMAIN/s: SPX, N-terminal (InterPro:IPR004331), Major facilitator superfamily MFS-1 (InterPro:IPR011701), Major facilitator superfamily, general substrate transporter (InterPro:IPR016196); BEST Arabidopsis thaliana protein match is: Major Facilitator Superfamily with SPX (SYG1/Pho81/XPR1) domain-containing protein (TAIR:AT4G11810.1).
    NP_567674.1
    • Major Facilitator Superfamily with SPX (SYG1/Pho81/XPR1) domain-containing protein; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: transmembrane transport; LOCATED IN: cellular_component unknown; CONTAINS InterPro DOMAIN/s: SPX, N-terminal (InterPro:IPR004331), Major facilitator superfamily MFS-1 (InterPro:IPR011701), Major facilitator superfamily, general substrate transporter (InterPro:IPR016196); BEST Arabidopsis thaliana protein match is: Major Facilitator Superfamily with SPX (SYG1/Pho81/XPR1) domain-containing protein (TAIR:AT4G11810.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      12048160..12051891 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001203876.2 → NP_001190805.1  Major Facilitator Superfamily with SPX (SYG1/Pho81/XPR1) domain-containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190805.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UUH7, A0A384KIR2, A0A654FRW9, F4JMQ7
      Conserved Domains (2) summary
      cd14479
      Location:2 → 141
      SPX-MFS_plant; SPX domain of proteins found in plants and stramenopiles; most have a C-terminal MFS domain
      cl28910
      Location:249 → 699
      MFS; Major Facilitator Superfamily

    2. NM_001341571.1 → NP_001328313.1  Major Facilitator Superfamily with SPX (SYG1/Pho81/XPR1) domain-containing protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UUH7, A0A384KIR2, A0A654FRW9, F4JMQ7
      Conserved Domains (2) summary
      cd14479
      Location:2 → 141
      SPX-MFS_plant; SPX domain of proteins found in plants and stramenopiles; most have a C-terminal MFS domain
      cl28910
      Location:249 → 699
      MFS; Major Facilitator Superfamily

    3. NM_118428.3 → NP_567674.1  Major Facilitator Superfamily with SPX (SYG1/Pho81/XPR1) domain-containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567674.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O82747, Q93ZQ5
      UniProtKB/TrEMBL
      A0A178UWJ9, A0A654FRW9
      Conserved Domains (4) summary
      cd06174
      Location:259 → 434
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      cd14479
      Location:2 → 141
      SPX-MFS_plant; SPX domain of proteins found in plants and stramenopiles; most have a C-terminal MFS domain
      pfam03105
      Location:4 → 145
      SPX; SPX domain
      pfam07690
      Location:256 → 642
      MFS_1; Major Facilitator Superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q93ZQ5.2

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