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    ABCB5 P-glycoprotein 5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 826974, updated on 18-Sep-2024

    Summary

    Official Symbol
    ABCB5
    Official Full Name
    P-glycoprotein 5
    Primary source
    TAIR:AT4G01830
    Locus tag
    AT4G01830
    See related
    Araport:AT4G01830
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATP-binding cassette B5; P-glycoprotein 5; PGP5; T7B11.9; T7B11_9
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    Genomic context

    See ABCB5 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    11
    Sequence:
    Chromosome: 4; NC_003075.7 (785551..790447, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Albino or Glassy Yellow 1 Neighboring gene Sec23/Sec24 protein transport family protein Neighboring gene P-glycoprotein 3 Neighboring gene Ca2+ activated outward rectifying K+ channel 5 Neighboring gene S-adenosylmethionine synthetase 2

    General gene information

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ABC-type transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATPase-coupled transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 

    General protein information

    Preferred Names
    P-glycoprotein 5
    NP_192092.1
    • P-glycoprotein 5 (PGP5); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances; INVOLVED IN: transport, transmembrane transport; LOCATED IN: integral to membrane; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: P-glycoprotein 3 (TAIR:AT4G01820.1); Has 845817 Blast hits to 392712 proteins in 4168 species: Archae - 14768; Bacteria - 661377; Metazoa - 18002; Fungi - 12658; Plants - 9684; Viruses - 32; Other Eukaryotes - 129296 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      785551..790447 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001340339.1NP_001329375.1  P-glycoprotein 5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V6D0, A0A1P8B7I4
    2. NM_116413.2NP_192092.1  P-glycoprotein 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_192092.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SYI3
      UniProtKB/TrEMBL
      A0A178V6D0
      Conserved Domains (3) summary
      cd03249
      Location:353591
      ABC_MTABC3_MDL1_MDL2; ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins
      PTZ00265
      Location:21224
      PTZ00265; multidrug resistance protein (mdr1); Provisional
      pfam00664
      Location:35293
      ABC_membrane; ABC transporter transmembrane region