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    SPP1 Phosphatidic acid phosphatase (PAP2) family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 825018, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SPP1
    Official Full Name
    Phosphatidic acid phosphatase (PAP2) family protein
    Primary source
    TAIR:AT3G58490
    Locus tag
    AT3G58490
    See related
    Araport:AT3G58490
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtSPP1; lipid phosphate phosphatase delta; LPPdelta; sphingoid phosphate phosphatase 1
    Summary
    Encodes a long-chain base 1-phosphate (LCBP) phosphatase that is expressed in the endoplasmic reticulum.
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    Genomic context

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    See SPP1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    8
    Sequence:
    Chromosome: 3; NC_003074.8 (21632812..21635178)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene RHOMBOID-like protein 15 Neighboring gene nucleic acid binding / methyltransferase Neighboring gene calmodulin-binding family protein Neighboring gene protein phosphatase 2A-4 Neighboring gene DEA(D/H)-box RNA helicase family protein Neighboring gene Ubiquitin carboxyl-terminal hydrolase family protein Neighboring gene RNI-like superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Degradation of long-chain base 1-phosphate (LCBP) in Arabidopsis: functional characterization of LCBP phosphatase involved in the dehydration stress response. Nakagawa N, et al. J Plant Res, 2012 May. PMID 21910031
    2. Involvement of sphingosine kinase in plant cell signalling. Worrall D, et al. Plant J, 2008 Oct. PMID 18557834, Free PMC Article
    3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    NM_001084839.2
    NM_115711.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables sphinganine-1-phosphate aldolase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables sphingosine-1-phosphate phosphatase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within response to abscisic acid IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within sphingolipid metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within stomatal closure IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Phosphatidic acid phosphatase (PAP2) family protein
    NP_001078308.1
    • Phosphatidic acid phosphatase (PAP2) family protein; FUNCTIONS IN: sphingosine-1-phosphate phosphatase activity, phosphoric ester hydrolase activity; INVOLVED IN: response to abscisic acid stimulus; LOCATED IN: endomembrane system, membrane; CONTAINS InterPro DOMAIN/s: Phosphatidic acid phosphatase type 2/haloperoxidase (InterPro:IPR000326); Has 1069 Blast hits to 1069 proteins in 384 species: Archae - 10; Bacteria - 625; Metazoa - 135; Fungi - 136; Plants - 31; Viruses - 0; Other Eukaryotes - 132 (source: NCBI BLink).
    NP_191408.1
    • Phosphatidic acid phosphatase (PAP2) family protein; FUNCTIONS IN: sphingosine-1-phosphate phosphatase activity, phosphoric ester hydrolase activity; INVOLVED IN: response to abscisic acid stimulus; LOCATED IN: membrane; CONTAINS InterPro DOMAIN/s: Phosphatidic acid phosphatase type 2/haloperoxidase (InterPro:IPR000326); Has 1219 Blast hits to 1219 proteins in 452 species: Archae - 20; Bacteria - 742; Metazoa - 137; Fungi - 144; Plants - 35; Viruses - 0; Other Eukaryotes - 141 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      21632812..21635178
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_115711.4 → NP_191408.1  Phosphatidic acid phosphatase (PAP2) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_191408.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M2G7
      UniProtKB/TrEMBL
      A0A178VD76, A0A654FIZ0
      Conserved Domains (1) summary
      PLN02525
      Location:72 → 416
      PLN02525; phosphatidic acid phosphatase family protein

    2. NM_001084839.2 → NP_001078308.1  Phosphatidic acid phosphatase (PAP2) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078308.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4J5V8, Q0WUC2
      Conserved Domains (2) summary
      PLN02525
      Location:1 → 346
      PLN02525; phosphatidic acid phosphatase family protein
      COG0671
      Location:77 → 165
      PgpB; Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M2G7.1

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