U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ADF2 actin depolymerizing factor 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 823743, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ADF2
    Official Full Name
    actin depolymerizing factor 2
    Primary source
    TAIR:AT3G46000
    Locus tag
    AT3G46000
    See related
    Araport:AT3G46000
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    actin depolymerizing factor 2
    Summary
    Encodes depolymerizing factor 2.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ADF2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    4
    Sequence:
    Chromosome: 3; NC_003074.8 (16907334..16909119, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Histone superfamily protein Neighboring gene Cofilin/tropomyosin-type actin-binding protein family Neighboring gene actin depolymerizing factor 1 Neighboring gene RNA-binding (RRM/RBD/RNP motifs) family protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Regulation of the pollen-specific actin-depolymerizing factor LlADF1. Allwood EG, et al. Plant Cell, 2002 Nov. PMID 12417710, Free PMC Article
    2. Actin-depolymerizing factor2-mediated actin dynamics are essential for root-knot nematode infection of Arabidopsis. Clément M, et al. Plant Cell, 2009 Sep. PMID 19794115, Free PMC Article
    3. Plant Actin-Depolymerizing Factors Possess Opposing Biochemical Properties Arising from Key Amino Acid Changes throughout Evolution. Nan Q, et al. Plant Cell, 2017 Feb. PMID 28123105, Free PMC Article
    4. High-throughput protein localization in Arabidopsis using Agrobacterium-mediated transient expression of GFP-ORF fusions. Koroleva OA, et al. Plant J, 2005 Jan. PMID 15610358
    5. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    NM_001339232.1
    NM_001339233.1
    NM_114469.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within actin filament depolymerization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in actin filament depolymerization IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 
    located_in nucleus HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    actin depolymerizing factor 2
    NP_566882.1
    • actin depolymerizing factor 2 (ADF2); FUNCTIONS IN: actin binding; INVOLVED IN: biological_process unknown; LOCATED IN: intracellular, nucleus, plasma membrane, cytoplasm; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Actin-binding, cofilin/tropomyosin type (InterPro:IPR002108); BEST Arabidopsis thaliana protein match is: actin depolymerizing factor 4 (TAIR:AT5G59890.1); Has 1494 Blast hits to 1493 proteins in 266 species: Archae - 0; Bacteria - 8; Metazoa - 650; Fungi - 147; Plants - 513; Viruses - 0; Other Eukaryotes - 176 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      16907334..16909119 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_114469.5 → NP_566882.1  actin depolymerizing factor 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566882.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39251, Q9LZT2
      UniProtKB/TrEMBL
      A0A178V7X3, A0A5S9XIC2
      Conserved Domains (1) summary
      cd11286
      Location:6 → 135
      ADF_cofilin_like; Cofilin, Destrin, and related actin depolymerizing factors

    2. NM_001339232.1 → NP_001327289.1  actin depolymerizing factor 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LRV3, A0A654FD75
      Conserved Domains (1) summary
      cl15697
      Location:23 → 154
      ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains

    3. NM_001339233.1 → NP_001327290.1  actin depolymerizing factor 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      C0Z352
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q39251.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.