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    PMH2 putative mitochondrial RNA helicase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821802, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PMH2
    Official Full Name
    putative mitochondrial RNA helicase 2
    Primary source
    TAIR:AT3G22330
    Locus tag
    AT3G22330
    See related
    Araport:AT3G22330
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATRH53; putative mitochondrial RNA helicase 2
    Summary
    DEAD-box protein required for efficient group II intron splicing in mitochondria.
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    Genomic context

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    See PMH2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    7
    Sequence:
    Chromosome: 3; NC_003074.8 (7892508..7895499)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene putative mitochondrial RNA helicase 1 Neighboring gene Eukaryotic rpb5 RNA polymerase subunit family protein Neighboring gene F-box/kelch-repeat protein Neighboring gene F-box/kelch-repeat protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Analysis of the Roles of the Arabidopsis nMAT2 and PMH2 Proteins Provided with New Insights into the Regulation of Group II Intron Splicing in Land-Plant Mitochondria. Zmudjak M, et al. Int J Mol Sci, 2017 Nov 17. PMID 29149092, Free PMC Article
    2. The DEAD-box protein PMH2 is required for efficient group II intron splicing in mitochondria of Arabidopsis thaliana. Köhler D, et al. Plant Mol Biol, 2010 Mar. PMID 19960362
    3. Two DEAD-box proteins may be part of RNA-dependent high-molecular-mass protein complexes in Arabidopsis mitochondria. Matthes A, et al. Plant Physiol, 2007 Dec. PMID 17951454, Free PMC Article
    4. Analysis of the Arabidopsis mitochondrial proteome. Millar AH, et al. Plant Physiol, 2001 Dec. PMID 11743115, Free PMC Article
    5. Proteomic analysis of the Arabidopsis nucleolus suggests novel nucleolar functions. Pendle AF, et al. Mol Biol Cell, 2005 Jan. PMID 15496452, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The nMAT2 and PMH2 function in the splicing of similar subsets of group II introns. The proteins may serve as components of a proto-spliceosomal complex in Arabidopsis plant mitochondria.
      Title: Analysis of the Roles of the Arabidopsis nMAT2 and PMH2 Proteins Provided with New Insights into the Regulation of Group II Intron Splicing in Land-Plant Mitochondria.
    2. PMH2 acts at the posttranscriptional level with a potential function as RNA chaperone required for formation or maintenance of complex RNA secondary structures of introns rather than a direct role in splicing.
      Title: The DEAD-box protein PMH2 is required for efficient group II intron splicing in mitochondria of Arabidopsis thaliana.
    3. PMH1 and PMH2 (for PUTATIVE MITOCHONDRIAL RNA HELICASE), were analyzed and characterized in mitochondria of Arabidopsis
      Title: Two DEAD-box proteins may be part of RNA-dependent high-molecular-mass protein complexes in Arabidopsis mitochondria.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_113131.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables RNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within Group II intron splicing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to cold IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 
    located_in mitochondrion HDA PubMed 
    located_in nucleolus HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plant-type cell wall HDA PubMed 
    part_of protein-containing complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    putative mitochondrial RNA helicase 2
    NP_188872.2
    • putative mitochondrial RNA helicase 2 (PMH2); FUNCTIONS IN: helicase activity, ATP-dependent helicase activity, ATP binding, nucleic acid binding; INVOLVED IN: response to cold, Group II intron splicing; LOCATED IN: mitochondrion, nucleolus, cell wall, protein complex; EXPRESSED IN: guard cell; CONTAINS InterPro DOMAIN/s: RNA helicase, DEAD-box type, Q motif (InterPro:IPR014014), DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: DEAD box RNA helicase (RH3) (TAIR:AT5G26742.2); Has 113280 Blast hits to 72794 proteins in 3598 species: Archae - 1390; Bacteria - 52148; Metazoa - 22767; Fungi - 9352; Plants - 8202; Viruses - 661; Other Eukaryotes - 18760 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      7892508..7895499
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_113131.5 → NP_188872.2  putative mitochondrial RNA helicase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_188872.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LUW5
      UniProtKB/TrEMBL
      A0A178VAK1, A0A5S9XEN2, A0A654FF04
      Conserved Domains (1) summary
      COG0513
      Location:107 → 480
      SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LUW5.1

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