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    NRPB5 Eukaryotic rpb5 RNA polymerase subunit family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821801, updated on 18-Sep-2024

    Summary

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    Official Symbol
    NRPB5
    Official Full Name
    Eukaryotic rpb5 RNA polymerase subunit family protein
    Primary source
    TAIR:AT3G22320
    Locus tag
    AT3G22320
    See related
    Araport:AT3G22320
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    A; ATRPABC24.3; NRPD5; RNA POLYMERASE II FIFTH LARGEST SUBUNIT; RPB5A
    Summary
    Non-catalytic subunit common to DNA-dependent RNA polymerases I, II, III and IV; homologous to budding yeast RPB5.
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    Genomic context

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    See NRPB5 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    5
    Sequence:
    Chromosome: 3; NC_003074.8 (7890803..7892349, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ribosomal protein S10 Neighboring gene putative mitochondrial RNA helicase 1 Neighboring gene putative mitochondrial RNA helicase 2 Neighboring gene F-box/kelch-repeat protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Interactions of the developmental regulator ABI3 with proteins identified from developing Arabidopsis seeds. Kurup S, et al. Plant J, 2000 Jan. PMID 10743655
    2. SHH1, a homeodomain protein required for DNA methylation, as well as RDR2, RDM4, and chromatin remodeling factors, associate with RNA polymerase IV. Law JA, et al. PLoS Genet, 2011 Jul. PMID 21811420, Free PMC Article
    3. Subunit compositions of the RNA-silencing enzymes Pol IV and Pol V reveal their origins as specialized forms of RNA polymerase II. Ream TS, et al. Mol Cell, 2009 Jan 30. PMID 19110459, Free PMC Article
    4. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_113130.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-directed 5'-3' RNA polymerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of RNA polymerase II, core complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of RNA polymerase IV complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Eukaryotic rpb5 RNA polymerase subunit family protein
    NP_188871.1
    • NRPB5; FUNCTIONS IN: DNA-directed RNA polymerase activity, DNA binding; INVOLVED IN: transcription; LOCATED IN: DNA-directed RNA polymerase II, core complex, DNA-directed RNA polymerase IV complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: RNA polymerase, Rpb5, N-terminal (InterPro:IPR005571), RNA polymerase, subunit H/Rpb5 C-terminal (InterPro:IPR000783), DNA-directed RNA polymerase, RPB5 subunit (InterPro:IPR014381), RNA polymerase, subunit H/Rpb5, conserved site (InterPro:IPR020608); BEST Arabidopsis thaliana protein match is: RNA polymerase II fifth largest subunit, C (TAIR:AT5G57980.1); Has 1046 Blast hits to 1046 proteins in 368 species: Archae - 260; Bacteria - 0; Metazoa - 162; Fungi - 216; Plants - 118; Viruses - 20; Other Eukaryotes - 270 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      7890803..7892349 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_113130.4 → NP_188871.1  Eukaryotic rpb5 RNA polymerase subunit family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_188871.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O81098
      UniProtKB/TrEMBL
      A0A178VI93, A0A5S9XF38
      Conserved Domains (1) summary
      PLN03111
      Location:1 → 205
      PLN03111; DNA-directed RNA polymerase II subunit family protein; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O81098.1

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