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    CDC27a Tetratricopeptide repeat (TPR)-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820879, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CDC27a
    Official Full Name
    Tetratricopeptide repeat (TPR)-like superfamily protein
    Primary source
    TAIR:AT3G16320
    Locus tag
    AT3G16320
    See related
    Araport:AT3G16320
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Summary
    Subunit in the anaphase-promoting complex. Role in gametogenesis, control of mitotic progression and cell differentiation during the entire life cycle.
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    Genomic context

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    See CDC27a in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    16
    Sequence:
    Chromosome: 3; NC_003074.8 (5529313..5534734)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein family (UPF0497) Neighboring gene mitotic phosphoprotein N' end (MPPN) family protein Neighboring gene Avr9/Cf-9 rapidly elicited protein Neighboring gene pleiotropic drug resistance 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Overexpression of the Arabidopsis anaphase promoting complex subunit CDC27a increases growth rate and organ size. Rojas CA, et al. Plant Mol Biol, 2009 Oct. PMID 19629716
    2. Specialization of CDC27 function in the Arabidopsis thaliana anaphase-promoting complex (APC/C). Pérez-Pérez JM, et al. Plant J, 2008 Jan. PMID 17944809
    3. The Arabidopsis anaphase-promoting complex or cyclosome: molecular and genetic characterization of the APC2 subunit. Capron A, et al. Plant Cell, 2003 Oct. PMID 14508008, Free PMC Article
    4. Targeted interactomics reveals a complex core cell cycle machinery in Arabidopsis thaliana. Van Leene J, et al. Mol Syst Biol, 2010 Aug 10. PMID 20706207, Free PMC Article
    5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Results indicate a role of AtCDC27a in regulation of plant growth.
      Title: Overexpression of the Arabidopsis anaphase promoting complex subunit CDC27a increases growth rate and organ size.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001338228.1
    NM_001338229.1
    NM_001338230.1
    NM_112503.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within gamete generation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of cell division IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of unidimensional cell growth IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of anaphase-promoting complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Tetratricopeptide repeat (TPR)-like superfamily protein
    NP_001319567.1
    • CDC27a; FUNCTIONS IN: binding; INVOLVED IN: regulation of cell division, cell cycle, gamete generation, regulation of unidimensional cell growth; LOCATED IN: anaphase-promoting complex; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: Tetratricopeptide TPR-1 (InterPro:IPR001440), Tetratricopeptide-like helical (InterPro:IPR011990), Tetratricopeptide repeat-containing (InterPro:IPR013026), Tetratricopeptide repeat (InterPro:IPR019734); BEST Arabidopsis thaliana protein match is: CDC27 family protein (TAIR:AT2G20000.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      5529313..5534734
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001338228.1 → NP_001319567.1  Tetratricopeptide repeat (TPR)-like superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A2H1ZEI2, A0A654F7Q9

    2. NM_112503.5 → NP_188253.3  Tetratricopeptide repeat (TPR)-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_188253.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O04325, Q06AN9, Q9LU16
      UniProtKB/TrEMBL
      A0A178VG51
      Conserved Domains (5) summary
      COG0457
      Location:381 → 650
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:489 → 517
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:489 → 522
      TPR_1; Tetratricopeptide repeat
      pfam12895
      Location:15 → 91
      ANAPC3; Anaphase-promoting complex, cyclosome, subunit 3
      pfam13414
      Location:629 → 690
      TPR_11; TPR repeat

    3. NM_001338229.1 → NP_001325497.1  Tetratricopeptide repeat (TPR)-like superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LLF0

    4. NM_001338230.1 → NP_001325498.1  Tetratricopeptide repeat (TPR)-like superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LLF1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q06AN9.2

    Gene LinkOut

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