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    GLU2 glutamate synthase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818721, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GLU2
    Official Full Name
    glutamate synthase 2
    Primary source
    TAIR:AT2G41220
    Locus tag
    AT2G41220
    See related
    Araport:AT2G41220
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F13H10.23; F13H10_23; glutamate synthase 2; GLUTAMATE SYNTHASE PRECURSOR
    Summary
    Encodes a gene whose sequence is similar to ferredoxin dependent glutamate synthase (Fd-GOGAT). Expression is most abundant in root.
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    Genomic context

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    See GLU2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    33
    Sequence:
    Chromosome: 2; NC_003071.7 (17177539..17188836)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene phosphatidylinositol- 4-phosphate 5-kinase 5 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene ORGAN SIZE-like protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation. Coschigano KT, et al. Plant Cell, 1998 May. PMID 9596633, Free PMC Article
    2. Identification of ubiquitinated proteins in Arabidopsis. Manzano C, et al. Plant Mol Biol, 2008 Sep. PMID 18535787
    3. Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis. Froehlich JE, et al. J Proteome Res, 2003 Jul-Aug. PMID 12938931
    4. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
    5. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_129687.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables glutamate synthase (ferredoxin) activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in L-glutamate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast envelope HDA PubMed 
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    glutamate synthase 2
    NP_181655.1
    • glutamate synthase 2 (GLU2); FUNCTIONS IN: glutamate synthase (ferredoxin) activity; INVOLVED IN: oxidation reduction, nitrogen compound metabolic process, glutamate biosynthetic process, metabolic process; LOCATED IN: chloroplast, chloroplast envelope; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Glutamine amidotransferase, class-II (InterPro:IPR000583), Glutamate synthase, alpha subunit, C-terminal (InterPro:IPR002489), Aldolase-type TIM barrel (InterPro:IPR013785), Glutamate synthase, central-N (InterPro:IPR006982), Glutamate synthase, central-C (InterPro:IPR002932), Glutamine amidotransferase, type II (InterPro:IPR017932); BEST Arabidopsis thaliana protein match is: glutamate synthase 1 (TAIR:AT5G04140.1); Has 17295 Blast hits to 17192 proteins in 1999 species: Archae - 278; Bacteria - 5572; Metazoa - 117; Fungi - 161; Plants - 174; Viruses - 0; Other Eukaryotes - 10993 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      17177539..17188836
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129687.5 → NP_181655.1  glutamate synthase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_181655.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O80665, Q9T0P4
      UniProtKB/TrEMBL
      A0A178VVG3, A0A5S9X6I4
      Conserved Domains (5) summary
      PRK11750
      Location:104 → 1598
      gltB; glutamate synthase subunit alpha; Provisional
      cd00982
      Location:1348 → 1598
      gltB_C; gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the ...
      cd02808
      Location:911 → 1306
      GltS_FMN; Glutamate synthase (GltS) FMN-binding domain. GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast ...
      pfam00310
      Location:108 → 530
      GATase_2; Glutamine amidotransferases class-II
      pfam04898
      Location:556 → 850
      Glu_syn_central; Glutamate synthase central domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9T0P4.2

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