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    MAPKKK17 mitogen-activated protein kinase kinase kinase 17 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817812, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MAPKKK17
    Official Full Name
    mitogen-activated protein kinase kinase kinase 17
    Primary source
    TAIR:AT2G32510
    Locus tag
    AT2G32510
    See related
    Araport:AT2G32510
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    mitogen-activated protein kinase kinase kinase 17; T26B15.7; T26B15_7
    Summary
    member of MEKK subfamily
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    Genomic context

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    See MAPKKK17 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    1
    Sequence:
    Chromosome: 2; NC_003071.7 (13798561..13800099, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene Stress responsive alpha-beta barrel domain protein Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene cellulose synthase-like B3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification and characterization of an ABA-activated MAP kinase cascade in Arabidopsis thaliana. Danquah A, et al. Plant J, 2015 Apr. PMID 25720833
    2. Wounding and Insect Feeding Trigger Two Independent MAPK Pathways with Distinct Regulation and Kinetics. Sözen C, et al. Plant Cell, 2020 Jun. PMID 32265268, Free PMC Article
    3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_128810.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables MAP kinase kinase kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein kinase binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in abscisic acid-activated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to abscisic acid IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to osmotic stress IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in signal transduction ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    mitogen-activated protein kinase kinase kinase 17
    NP_180810.1
    • mitogen-activated protein kinase kinase kinase 17 (MAPKKK17); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; EXPRESSED IN: 7 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: mitogen-activated protein kinase kinase kinase 18 (TAIR:AT1G05100.1); Has 127064 Blast hits to 125367 proteins in 4754 species: Archae - 157; Bacteria - 14643; Metazoa - 47323; Fungi - 12478; Plants - 31679; Viruses - 660; Other Eukaryotes - 20124 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      13798561..13800099 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128810.2 → NP_180810.1  mitogen-activated protein kinase kinase kinase 17 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180810.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O80888
      UniProtKB/TrEMBL
      A0A178VW07, A0A5S9X3A6, A0A654EZK4
      Conserved Domains (1) summary
      cd06606
      Location:2 → 259
      STKc_MAPKKK; Catalytic domain of the Serine/Threonine Kinase, Mitogen-Activated Protein Kinase Kinase Kinase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O80888.1

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