ABI4 Integrase-type DNA-binding superfamily protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: ABI4
Official Full Name: Integrase-type DNA-binding superfamily protein
Primary source: TAIR:AT2G40220
Locus tag: AT2G40220
See related: Araport:AT2G40220
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ABA INSENSITIVE 4; ABSCISIC ACID-INSENSITIVE PROTEIN 4; ATABI4; GIN6; GLUCOSE INSENSITIVE 6; IMPAIRED SUCROSE INDUCTION 3; ISI3; SALOBRENO 5; SAN5; SIS5; SUCROSE UNCOUPLED 6; SUGAR-INSENSITIVE 5; SUN6; T7M7.16
Summary: Encodes a member of the DREB subfamily A-3 of ERF/AP2 transcription factor family (ABI4). The protein contains one AP2 domain. There is only one member in this family. Involved in abscisic acid (ABA) signal transduction, ABA-mediated glucose response, and hexokinase-dependent sugar responses. Acts downstream of GUN1 in retrograde signaling. Expressed most abundantly in developing siliques and to a lesser degree in seedlings.
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Genomic context

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See ABI4 in Genome Data Viewer

Location:: chromosome: 2

Exon count:: 1

Sequence:: Chromosome: 2; NC_003071.7 (16796247..16797585, complement)

Chromosome 2 - NC_003071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Stomatal regulation: Role of H2S-induced persulfidation in ABA signaling.
Title: Stomatal regulation: Role of H(2)S-induced persulfidation in ABA signaling.
Hydrogen sulfide-linked persulfidation of ABI4 controls ABA responses through the transactivation of MAPKKK18 in Arabidopsis.
Title: Hydrogen sulfide-linked persulfidation of ABI4 controls ABA responses through the transactivation of MAPKKK18 in Arabidopsis.
Arabidopsis OXS3 family proteins repress ABA signaling through interactions with AFP1 in the regulation of ABI4 expression.
Title: Arabidopsis OXS3 family proteins repress ABA signaling through interactions with AFP1 in the regulation of ABI4 expression.
AtMYB32 regulates the ABA response by targeting ABI3, ABI4 and ABI5 and the drought response by targeting CBF4 in Arabidopsis.
Title: AtMYB32 regulates the ABA response by targeting ABI3, ABI4 and ABI5 and the drought response by targeting CBF4 in Arabidopsis.
The Arabidopsis transcription factor LBD15 mediates ABA signaling and tolerance of water-deficit stress by regulating ABI4 expression.
Title: The Arabidopsis transcription factor LBD15 mediates ABA signaling and tolerance of water-deficit stress by regulating ABI4 expression.
A Kinase-Phosphatase-Transcription Factor Module Regulates Adventitious Root Emergence in Arabidopsis Root-Hypocotyl Junctions.
Title: A Kinase-Phosphatase-Transcription Factor Module Regulates Adventitious Root Emergence in Arabidopsis Root-Hypocotyl Junctions.
Abscisic acid positively regulates l-arabinose metabolism to inhibit seed germination through ABSCISIC ACID INSENSITIVE4-mediated transcriptional promotions of MUR4 in Arabidopsis thaliana.
Title: Abscisic acid positively regulates l-arabinose metabolism to inhibit seed germination through ABSCISIC ACID INSENSITIVE4-mediated transcriptional promotions of MUR4 in Arabidopsis thaliana.
ABI4 is not involved in biogenic chloroplast-to-nucleus retrograde signaling.
Title: Plastid-to-Nucleus Retrograde Signalling during Chloroplast Biogenesis Does Not Require ABI4.
The findings show that a novel ATX5-HY1-ABI4 module controls the glucose response in Arabidopsis thaliana.
Title: Trithorax-group protein ATX5 mediates the glucose response via impacting the HY1-ABI4 signaling module.
Compared to the wild-type (Col-0) Arabidopsis thaliana plants, the abi4 mutant demonstrated increased susceptibility to two-spotted spider mite, reflected as enhanced female fecundity and greater frequency of mite leaf damage after trypan blue staining.
Title: Abscisic Acid Insensitive 4 transcription factor is an important player in the response of Arabidopsis thaliana to two-spotted spider mite (Tetranychus urticae) feeding.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_129580.2

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables DNA-binding transcription factor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables DNA-binding transcription factor activity	TAS Traceable Author Statement more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables sequence-specific DNA binding	IPI Inferred from Physical Interaction more info	PubMed
enables transcription cis-regulatory region binding	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within abscisic acid-activated signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within hexokinase-dependent signaling	NAS Non-traceable Author Statement more info
acts_upstream_of_or_within lateral root development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within mitochondria-nucleus signaling pathway	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within mitochondria-nucleus signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within positive regulation of DNA-templated transcription	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within regulation of DNA-templated transcription	TAS Traceable Author Statement more info	PubMed
acts_upstream_of_or_within regulation of L-ascorbic acid biosynthetic process	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within regulation of protein localization	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within regulation of stomatal movement	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within regulation of triglyceride catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to glucose	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to osmotic stress	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to sucrose	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within response to trehalose	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to water deprivation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within root meristem growth	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within seed development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within starch catabolic process	NAS Non-traceable Author Statement more info	PubMed
acts_upstream_of_or_within sugar mediated signaling pathway	TAS Traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: Integrase-type DNA-binding superfamily protein

NP_181551.1

ABA INSENSITIVE 4 (ABI4); CONTAINS InterPro DOMAIN/s: DNA-binding, integrase-type (InterPro:IPR016177), Pathogenesis-related transcriptional factor/ERF, DNA-binding (InterPro:IPR001471); BEST Arabidopsis thaliana protein match is: Integrase-type DNA-binding superfamily protein (TAIR:AT3G57600.1); Has 5833 Blast hits to 5755 proteins in 285 species: Archae - 0; Bacteria - 4; Metazoa - 56; Fungi - 8; Plants - 5653; Viruses - 6; Other Eukaryotes - 106 (source: NCBI BLink).