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    CYP88A3 cytochrome P450, family 88, subfamily A, polypeptide 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839311, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CYP88A3
    Official Full Name
    cytochrome P450, family 88, subfamily A, polypeptide 3
    Primary source
    TAIR:AT1G05160
    Locus tag
    AT1G05160
    See related
    Araport:AT1G05160
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ''cytochrome P450; ATKAO1; cytochrome P450; ENT-KAURENOIC ACID OXYDASE 1; family 88; KAO1; polypeptide 3; polypeptide 3''; subfamily A; YUP8H12.23; YUP8H12_23
    Summary
    Encodes an ent-kaurenoic acid hydroxylase, a member of the CYP88A cytochrome p450 family.
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    Genomic context

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    See CYP88A3 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    9
    Sequence:
    Chromosome: 1; NC_003070.9 (1487378..1491005, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Peptidase M50 family protein Neighboring gene Calcium-binding tetratricopeptide family protein Neighboring gene Galactosyltransferase family protein Neighboring gene ncRNA Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The gibberellin biosynthetic genes AtKAO1 and AtKAO2 have overlapping roles throughout Arabidopsis development. Regnault T, et al. Plant J, 2014 Nov. PMID 25146977
    2. A plastid envelope location of Arabidopsis ent-kaurene oxidase links the plastid and endoplasmic reticulum steps of the gibberellin biosynthesis pathway. Helliwell CA, et al. Plant J, 2001 Oct. PMID 11722763
    3. The CYP88A cytochrome P450, ent-kaurenoic acid oxidase, catalyzes three steps of the gibberellin biosynthesis pathway. Helliwell CA, et al. Proc Natl Acad Sci U S A, 2001 Feb 13. PMID 11172076, Free PMC Article
    4. The involvement of gibberellin 20-oxidase genes in phytochrome-regulated petiole elongation of Arabidopsis. Hisamatsu T, et al. Plant Physiol, 2005 Jun. PMID 15923331, Free PMC Article
    5. Identification and characterization of nuclear pore complex components in Arabidopsis thaliana. Tamura K, et al. Plant Cell, 2010 Dec. PMID 21189294, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001331521.1
    NM_100394.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ent-kaurenoic acid monooxygenase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in gibberellin biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within gibberellin biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cytochrome P450, family 88, subfamily A, polypeptide 3
    NP_172008.1
    • ''cytochrome P450, family 88, subfamily A, polypeptide 3'' (CYP88A3); CONTAINS InterPro DOMAIN/s: Cytochrome P450, B-class (InterPro:IPR002397), Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, conserved site (InterPro:IPR017972); BEST Arabidopsis thaliana protein match is: ent-kaurenoic acid hydroxylase 2 (TAIR:AT2G32440.2); Has 36129 Blast hits to 36053 proteins in 1833 species: Archae - 82; Bacteria - 8530; Metazoa - 11168; Fungi - 6175; Plants - 8031; Viruses - 6; Other Eukaryotes - 2137 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      1487378..1491005 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100394.4 → NP_172008.1  cytochrome P450, family 88, subfamily A, polypeptide 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_172008.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23051, Q9C5Y3
      UniProtKB/TrEMBL
      A0A178W8Z7, A0A654E8Z2, Q0WPQ3
      Conserved Domains (1) summary
      PLN02302
      Location:3 → 490
      PLN02302; ent-kaurenoic acid oxidase

    2. NM_001331521.1 → NP_001320198.1  cytochrome P450, family 88, subfamily A, polypeptide 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23051, Q9C5Y3
      UniProtKB/TrEMBL
      A0A178W8Z7, A0A654E8Z2, Q0WPQ3
      Conserved Domains (1) summary
      PLN02302
      Location:3 → 490
      PLN02302; ent-kaurenoic acid oxidase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O23051.1

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