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    LAP6 Chalcone and stilbene synthase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839280, updated on 18-Sep-2024

    Summary

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    Official Symbol
    LAP6
    Official Full Name
    Chalcone and stilbene synthase family protein
    Primary source
    TAIR:AT1G02050
    Locus tag
    AT1G02050
    See related
    Araport:AT1G02050
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    LESS ADHESIVE POLLEN 6; polyketide synthase A; PSKA; T7I23.4; T7I23_4
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    Genomic context

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    See LAP6 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    2
    Sequence:
    Chromosome: 1; NC_003070.9 (359117..360746, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene nitroreductase family protein Neighboring gene C2H2-like zinc finger protein Neighboring gene C2H2-type zinc finger family protein Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene squamosa promoter binding protein-like 8 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. LAP6/POLYKETIDE SYNTHASE A and LAP5/POLYKETIDE SYNTHASE B encode hydroxyalkyl α-pyrone synthases required for pollen development and sporopollenin biosynthesis in Arabidopsis thaliana. Kim SS, et al. Plant Cell, 2010 Dec. PMID 21193570, Free PMC Article
    2. LAP5 and LAP6 encode anther-specific proteins with similarity to chalcone synthase essential for pollen exine development in Arabidopsis. Dobritsa AA, et al. Plant Physiol, 2010 Jul. PMID 20442277, Free PMC Article
    3. Sporopollenin biosynthetic enzymes interact and constitute a metabolon localized to the endoplasmic reticulum of tapetum cells. Lallemand B, et al. Plant Physiol, 2013 Jun. PMID 23632852, Free PMC Article
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. At1g02050 interacts and constitutes a part of metabolon localized to the endoplasmic reticulum of tapetum cells.At1g02050 is sporopollenin biosynthetic enzyme.
      Title: Sporopollenin biosynthetic enzymes interact and constitute a metabolon localized to the endoplasmic reticulum of tapetum cells.
    2. results show hydroxylated alpha-pyrone polyketide compounds generated by the sequential action of ACOS5 and LAP6/LAP5 are potential and previously unknown sporopollenin precursors
      Title: LAP6/POLYKETIDE SYNTHASE A and LAP5/POLYKETIDE SYNTHASE B encode hydroxyalkyl α-pyrone synthases required for pollen development and sporopollenin biosynthesis in Arabidopsis thaliana.
    3. LAP5 and LAP6 are multifunctional enzymes and may play a role in both the synthesis of pollen fatty acids and phenolics found in exine.[LAP6]
      Title: LAP5 and LAP6 encode anther-specific proteins with similarity to chalcone synthase essential for pollen exine development in Arabidopsis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    NM_100085.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables tetraketide alpha-pyrone synthase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in flavonoid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within pollen exine formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within polyketide biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within sporopollenin biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Chalcone and stilbene synthase family protein
    NP_171707.1
    • LESS ADHESIVE POLLEN 6 (LAP6); FUNCTIONS IN: transferase activity, transferring acyl groups other than amino-acyl groups, catalytic activity, acyltransferase activity; INVOLVED IN: phenylpropanoid biosynthetic process, pollen exine formation; EXPRESSED IN: 11 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Chalcone/stilbene synthase, N-terminal (InterPro:IPR001099), Thiolase-like (InterPro:IPR016039), Polyketide synthase, type III (InterPro:IPR011141), Thiolase-like, subgroup (InterPro:IPR016038), Chalcone/stilbene synthase, C-terminal (InterPro:IPR012328); BEST Arabidopsis thaliana protein match is: Chalcone and stilbene synthase family protein (TAIR:AT4G00040.1); Has 6482 Blast hits to 6477 proteins in 1606 species: Archae - 0; Bacteria - 2500; Metazoa - 0; Fungi - 67; Plants - 3666; Viruses - 0; Other Eukaryotes - 249 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      359117..360746 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100085.4 → NP_171707.1  Chalcone and stilbene synthase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_171707.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23674, Q4JNW9
      UniProtKB/TrEMBL
      A0A178WKY7, A0A5S9S5U4, A0A654E665
      Conserved Domains (1) summary
      PLN03169
      Location:5 → 394
      PLN03169; chalcone synthase family protein; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O23674.1

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