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    PTAC4 plastid transcriptionally active 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842833, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PTAC4
    Official Full Name
    plastid transcriptionally active 4
    Primary source
    TAIR:AT1G65260
    Locus tag
    AT1G65260
    See related
    Araport:AT1G65260
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    plastid transcriptionally active 4; T8F5.2; T8F5_2; VESICLE-INDUCING PROTEIN IN PLASTIDS 1; VIPP1
    Summary
    Encodes a protein required for thylakoid membrane formation.
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    Genomic context

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    See PTAC4 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    11
    Sequence:
    Chromosome: 1; NC_003070.9 (24236088..24240728)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene transmembrane protein, putative (DUF2358) Neighboring gene Eukaryotic aspartyl protease family protein Neighboring gene Protein kinase superfamily protein Neighboring gene ER membrane protein complex subunit-like protein Neighboring gene DNAJ heat shock N-terminal domain-containing protein Neighboring gene mitochondrial acyl carrier protein 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. VIPP1 Involved in Chloroplast Membrane Integrity Has GTPase Activity in Vitro. Ohnishi N, et al. Plant Physiol, 2018 May. PMID 29622686, Free PMC Article
    2. Essential role of VIPP1 in chloroplast envelope maintenance in Arabidopsis. Zhang L, et al. Plant Cell, 2012 Sep. PMID 23001039, Free PMC Article
    3. The first α-helical domain of the vesicle-inducing protein in plastids 1 promotes oligomerization and lipid binding. Otters S, et al. Planta, 2013 Feb. PMID 23053543
    4. VIPP1 Has a Disordered C-Terminal Tail Necessary for Protecting Photosynthetic Membranes against Stress. Zhang L, et al. Plant Physiol, 2016 Jul. PMID 27208228, Free PMC Article
    5. Specific interaction of IM30/Vipp1 with cyanobacterial and chloroplast membranes results in membrane remodeling and eventually in membrane fusion. Heidrich J, et al. Biochim Biophys Acta Biomembr, 2017 Apr. PMID 27693914

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Although VIPP1 does not contain a canonical G domain, the amino-terminal alpha-helix was found to be important for both GTP binding and GTP hydrolysis as well as for oligomer formation.
      Title: VIPP1 Involved in Chloroplast Membrane Integrity Has GTPase Activity in Vitro.
    2. VIPP1 is involved in the maintenance of photosynthetic membranes.VIPP1 intrinsically disordered tail is necessary to maintain its function against heat stress recovery.
      Title: VIPP1 Has a Disordered C-Terminal Tail Necessary for Protecting Photosynthetic Membranes against Stress.
    3. Specific interaction of Vipp1 with cyanobacterial and chloroplast membranes results in membrane remodeling and eventually in membrane fusion. (Review)
      Title: Specific interaction of IM30/Vipp1 with cyanobacterial and chloroplast membranes results in membrane remodeling and eventually in membrane fusion.
    4. AtHsp90.5 may help in the disassembly of VIPP1 for thylakoid membrane formation and/or maintenance.
      Title: Chloroplast-targeted Hsp90 plays essential roles in plastid development and embryogenesis in Arabidopsis possibly linking with VIPP1.
    5. VIPP1 is a multifunctional protein in chloroplasts that is critically important for envelope maintenance.
      Title: Essential role of VIPP1 in chloroplast envelope maintenance in Arabidopsis.
    6. Vipp1 domains are involved in homo-oligomerization as well as association with chloroplast inner envelope membranes.
      Title: The first α-helical domain of the vesicle-inducing protein in plastids 1 promotes oligomerization and lipid binding.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_105199.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within thylakoid membrane organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within vesicle organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast envelope HDA PubMed 
    located_in chloroplast nucleoid HDA PubMed 
    located_in chloroplast stroma HDA PubMed 
    located_in chloroplast thylakoid HDA PubMed 
    located_in chloroplast thylakoid membrane HDA PubMed 
    located_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    plastid transcriptionally active 4
    NP_564846.1
    • plastid transcriptionally active 4 (PTAC4); INVOLVED IN: vesicle organization, thylakoid membrane organization; LOCATED IN: in 8 components; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: PspA/IM30 (InterPro:IPR007157); Has 3123 Blast hits to 3108 proteins in 1139 species: Archae - 38; Bacteria - 2412; Metazoa - 160; Fungi - 68; Plants - 89; Viruses - 95; Other Eukaryotes - 261 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      24236088..24240728
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001334199.1 → NP_001322349.1  plastid transcriptionally active 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W0D3, A0A1P8ATS2, A0A384L5D6, A0A7G2E3F7

    2. NM_105199.3 → NP_564846.1  plastid transcriptionally active 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564846.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O80796
      UniProtKB/TrEMBL
      A0A654EMV2
      Conserved Domains (1) summary
      COG1842
      Location:72 → 290
      PspA; Phage shock protein A [Transcription, Signal transduction mechanisms]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O80796.1

    Gene LinkOut

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