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    Terpenoid cyclases family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 844186, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Terpenoid cyclases family protein
    Primary source
    TAIR:AT1G78500
    Locus tag
    AT1G78500
    See related
    Araport:AT1G78500
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    PEN6; PENTACYCLIC TRITERPENE SYNTHASE 6; T30F21.16; T30F21_16
    Summary
    Encodes a protein with pentacyclic triterpene synthase activity. In addition to the compounds lupeol, alpha-amyrin and bauerenol, this enzyme was also shown to produce two <i>seco</i>-triterpenes: alpha- and beta-<i>seco</i>-amyrin.
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    15
    Sequence:
    Chromosome: 1; NC_003070.9 (29531467..29535204)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Prenyltransferase family protein Neighboring gene cytochrome P450, family 708, subfamily A, polypeptide 3 Neighboring gene solanesyl diphosphate synthase 1 Neighboring gene Carbohydrate-binding X8 domain superfamily protein Neighboring gene Protein kinase superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Origin of structural diversity in natural triterpenes: direct synthesis of seco-triterpene skeletons by oxidosqualene cyclase. Shibuya M, et al. J Am Chem Soc, 2007 Feb 7. PMID 17263431
    2. Molecular cloning and expression in yeast of 2,3-oxidosqualene-triterpenoid cyclases from Arabidopsis thaliana. Husselstein-Muller T, et al. Plant Mol Biol, 2001 Jan. PMID 11247608
    3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables lupeol synthase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables oxidosqualene cyclase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in triterpenoid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in lipid droplet IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Terpenoid cyclases family protein
    NP_177971.1
    • Terpenoid cyclases family protein; CONTAINS InterPro DOMAIN/s: Terpene synthase, conserved site (InterPro:IPR002365), Terpenoid cylases/protein prenyltransferase alpha-alpha toroid (InterPro:IPR008930), Squalene cyclase (InterPro:IPR018333), Prenyltransferase/squalene oxidase (InterPro:IPR001330); BEST Arabidopsis thaliana protein match is: baruol synthase 1 (TAIR:AT4G15370.1); Has 1985 Blast hits to 1925 proteins in 565 species: Archae - 4; Bacteria - 842; Metazoa - 93; Fungi - 239; Plants - 602; Viruses - 0; Other Eukaryotes - 205 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      29531467..29535204
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001334828.1 → NP_001322480.1  Terpenoid cyclases family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SYN1
      UniProtKB/TrEMBL
      A0A5S9WVG9, A0A654EQB4
      Conserved Domains (1) summary
      PLN03012
      Location:1 → 766
      PLN03012; Camelliol C synthase

    2. NM_106497.1 → NP_177971.1  Terpenoid cyclases family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177971.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SYN1
      UniProtKB/TrEMBL
      A0A5S9WVG9, A0A654EQB4
      Conserved Domains (1) summary
      PLN03012
      Location:1 → 766
      PLN03012; Camelliol C synthase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SYN1.1

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