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    zinc ion binding/nucleic acid binding/hydrolase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841256, updated on 18-Sep-2024

    Summary

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    Official Full Name
    zinc ion binding/nucleic acid binding/hydrolase
    Primary source
    TAIR:AT1G48360
    Locus tag
    AT1G48360
    See related
    Araport:AT1G48360
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F11A17.9; F11A17_9
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    14
    Sequence:
    Chromosome: 1; NC_003070.9 (17868522..17873261)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene Ribosomal L18p/L5e family protein Neighboring gene uncharacterized protein Neighboring gene YELLOW STRIPE like 8 Neighboring gene root hair initiation protein root hairless 1 (RHL1) Neighboring gene RNI-like superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The nuclease FAN1 is involved in DNA crosslink repair in Arabidopsis thaliana independently of the nuclease MUS81. Herrmann NJ, et al. Nucleic Acids Res, 2015 Apr 20. PMID 25779053, Free PMC Article
    2. The RecQ-like helicase HRQ1 is involved in DNA crosslink repair in Arabidopsis in a common pathway with the Fanconi anemia-associated nuclease FAN1 and the postreplicative repair ATPase RAD5A. Röhrig S, et al. New Phytol, 2018 Jun. PMID 29577315
    3. Arabidopsis thaliana FANCD2 Promotes Meiotic Crossover Formation. Kurzbauer MT, et al. Plant Cell, 2018 Feb. PMID 29352063, Free PMC Article
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001123975.2
    NM_001333325.1
    NM_001333326.1
    NM_001333327.1
    NM_001333328.1
    NM_103732.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphodiesterase I activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    NOT involved_in double-strand break repair via homologous recombination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within homologous chromosome pairing at meiosis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in interstrand cross-link repair IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within interstrand cross-link repair IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within interstrand cross-link repair IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    zinc ion binding/nucleic acid binding/hydrolase
    NP_001117447.1
    • zinc ion binding;nucleic acid binding;hydrolases, acting on acid anhydrides, in phosphorus-containing anhydrides; FUNCTIONS IN: hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, zinc ion binding, nucleic acid binding; INVOLVED IN: biological_process unknown; LOCATED IN: mitochondrion; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: HIP116, Rad5p N-terminal (InterPro:IPR014905), VRR-NUC (InterPro:IPR014883); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_001319172.1
    • zinc ion binding;nucleic acid binding;hydrolases, acting on acid anhydrides, in phosphorus-containing anhydrides; FUNCTIONS IN: hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, zinc ion binding, nucleic acid binding; INVOLVED IN: biological_process unknown; LOCATED IN: mitochondrion; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: HIP116, Rad5p N-terminal (InterPro:IPR014905); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_175269.2
    • zinc ion binding;nucleic acid binding;hydrolases, acting on acid anhydrides, in phosphorus-containing anhydrides; FUNCTIONS IN: hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, zinc ion binding, nucleic acid binding; INVOLVED IN: biological_process unknown; LOCATED IN: mitochondrion; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: HIP116, Rad5p N-terminal (InterPro:IPR014905); Has 572 Blast hits to 551 proteins in 242 species: Archae - 0; Bacteria - 261; Metazoa - 71; Fungi - 95; Plants - 95; Viruses - 0; Other Eukaryotes - 50 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      17868522..17873261
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_103732.3 → NP_175269.2  zinc ion binding/nucleic acid binding/hydrolase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_175269.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2E2F7
      Conserved Domains (1) summary
      pfam08797
      Location:159 → 249
      HIRAN; HIRAN domain

    2. NM_001123975.2 → NP_001117447.1  zinc ion binding/nucleic acid binding/hydrolase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001117447.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q5XVJ4, Q5XVJ5, Q9SX69
      UniProtKB/TrEMBL
      A0A7G2E2F7
      Conserved Domains (2) summary
      pfam08774
      Location:769 → 885
      VRR_NUC; VRR-NUC domain
      pfam08797
      Location:159 → 249
      HIRAN; HIRAN domain

    3. NM_001333327.1 → NP_001323022.1  zinc ion binding/nucleic acid binding/hydrolase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AVV1

    4. NM_001333326.1 → NP_001323020.1  zinc ion binding/nucleic acid binding/hydrolase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AVS5

    5. NM_001333328.1 → NP_001323021.1  zinc ion binding/nucleic acid binding/hydrolase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AVS9

    6. NM_001333325.1 → NP_001319172.1  zinc ion binding/nucleic acid binding/hydrolase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q5XVJ4
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5XVJ4.2

    Gene LinkOut

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