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    sodium/calcium exchanger family protein / calcium-binding EF hand family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841755, updated on 18-Sep-2024

    Summary

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    Official Full Name
    sodium/calcium exchanger family protein / calcium-binding EF hand family protein
    Primary source
    TAIR:AT1G53210
    Locus tag
    AT1G53210
    See related
    Araport:AT1G53210
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtNCL; F12M16.12; F12M16_12; Na+/Ca2+ exchanger; NCL
    Summary
    Encodes a Na+/Ca 2+ exchanger-like protein that participates in the maintenance of Ca 2+ homeostasis.
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    7
    Sequence:
    Chromosome: 1; NC_003070.9 (19844450..19847856)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene RING/U-box superfamily protein Neighboring gene TAF RNA polymerase I subunit A Neighboring gene tRNA-Ile Neighboring gene ncRNA Neighboring gene TEOSINTE BRANCHED 1, cycloidea and PCF transcription factor 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Ca(2+) -regulated and diurnal rhythm-regulated Na(+) /Ca(2+) exchanger AtNCL affects flowering time and auxin signalling in Arabidopsis. Li P, et al. Plant Cell Environ, 2016 Feb. PMID 26296956
    2. A Na+/Ca2+ exchanger-like protein (AtNCL) involved in salt stress in Arabidopsis. Wang P, et al. J Biol Chem, 2012 Dec 28. PMID 23148213, Free PMC Article
    3. Large-scale characterization of integral proteins from Arabidopsis vacuolar membrane by two-dimensional liquid chromatography. Szponarski W, et al. Proteomics, 2004 Feb. PMID 14760709
    4. Mapping the Arabidopsis organelle proteome. Dunkley TP, et al. Proc Natl Acad Sci U S A, 2006 Apr 25. PMID 16618929, Free PMC Article
    5. The vegetative vacuole proteome of Arabidopsis thaliana reveals predicted and unexpected proteins. Carter C, et al. Plant Cell, 2004 Dec. PMID 15539469, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AtNCL is a vacuolar Ca(2+) -regulated Na(+) /Ca(2+) exchanger that regulates auxin responses and flowering time.
      Title: Ca(2+) -regulated and diurnal rhythm-regulated Na(+) /Ca(2+) exchanger AtNCL affects flowering time and auxin signalling in Arabidopsis.
    2. AtNCL (At1g53210)participates in the maintenance of Ca(2+) homeostasis.
      Title: A Na+/Ca2+ exchanger-like protein (AtNCL) involved in salt stress in Arabidopsis.
    Submit: New GeneRIF Correction

    General gene information

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    NM_104200.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables calcium ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables calcium:sodium antiporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within calcium ion homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cellular response to salt stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plant-type vacuole HDA PubMed 
    located_in plasmodesma HDA PubMed 
    located_in vacuolar membrane HDA PubMed 
    located_in vacuole HDA PubMed 

    General protein information

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    Preferred Names
    sodium/calcium exchanger family protein / calcium-binding EF hand family protein
    NP_564623.2
    • sodium/calcium exchanger family protein / calcium-binding EF hand family protein; FUNCTIONS IN: calcium ion binding; INVOLVED IN: transmembrane transport; LOCATED IN: vacuolar membrane, plasma membrane, vacuole, membrane, plant-type vacuole; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: EF-Hand 1, calcium-binding site (InterPro:IPR018247), Sodium/calcium exchanger membrane region (InterPro:IPR004837), EF-HAND 2 (InterPro:IPR018249), EF-hand-like domain (InterPro:IPR011992), Calcium-binding EF-hand (InterPro:IPR002048); BEST Arabidopsis thaliana protein match is: Calcium-binding EF-hand family protein (TAIR:AT1G29020.1); Has 622 Blast hits to 603 proteins in 166 species: Archae - 12; Bacteria - 69; Metazoa - 8; Fungi - 194; Plants - 285; Viruses - 0; Other Eukaryotes - 54 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      19844450..19847856
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104200.3 → NP_564623.2  sodium/calcium exchanger family protein / calcium-binding EF hand family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564623.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q67ZY8, Q8L636, Q9ASV9, Q9MAH9
      UniProtKB/TrEMBL
      A0A178W2M7, A0A5S9WLW0, A0A7G2E1X1
      Conserved Domains (2) summary
      pfam01699
      Location:448 → 576
      Na_Ca_ex; Sodium/calcium exchanger protein
      pfam13499
      Location:303 → 369
      EF-hand_7; EF-hand domain pair
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8L636.1

    Gene LinkOut

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