IGMT5 O-methyltransferase family protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: IGMT5
Official Full Name: O-methyltransferase family protein
Primary source: TAIR:AT1G76790
Locus tag: AT1G76790
See related: Araport:AT1G76790
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F28O16.16; F28O16_16; indole glucosinolate O-methyltransferase 5
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Genomic context

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See IGMT5 in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 3

Sequence:: Chromosome: 1; NC_003070.9 (28822186..28823727, complement)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Disruption of IGMT5 function increases resistance against the root-knot nematode Meloidogyne javanica.
Title: Methyl Transfer in Glucosinolate Biosynthesis Mediated by Indole Glucosinolate O-Methyltransferase 5.

Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_106329.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables O-methyltransferase activity	IMP Inferred from Mutant Phenotype more info	PubMed
NOT enables acetylserotonin O-methyltransferase activity	IDA Inferred from Direct Assay more info	PubMed
enables protein dimerization activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within indole glucosinolate biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	TAS Traceable Author Statement more info	PubMed

General protein information

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Preferred Names: O-methyltransferase family protein

NP_177805.1

O-methyltransferase family protein; FUNCTIONS IN: methyltransferase activity, O-methyltransferase activity, protein dimerization activity; LOCATED IN: cytosol; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Plant methyltransferase dimerisation (InterPro:IPR012967), O-methyltransferase, family 2 (InterPro:IPR001077), O-methyltransferase, COMT, eukaryota (InterPro:IPR016461); BEST Arabidopsis thaliana protein match is: O-methyltransferase family protein (TAIR:AT1G21100.1); Has 3410 Blast hits to 3406 proteins in 587 species: Archae - 1; Bacteria - 1002; Metazoa - 109; Fungi - 633; Plants - 1541; Viruses - 0; Other Eukaryotes - 124 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

28822186..28823727 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_106329.3 → NP_177805.1 O-methyltransferase family protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_177805.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q8L931, Q9SRD4

UniProtKB/TrEMBL

A0A178WFJ3, A0A5S9WUY0

Conserved Domains (2) summary

pfam08100
Location:30 → 89

dimerization; dimerization domain

cl17173
Location:142 → 347

AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...